Results 261 to 270 of about 44,382 (319)
ABSTRACT Ectopic ACTH secretion‐related Cushing's syndrome may manifest as a rapid onset of hypercortisolism, elevated urinary free cortisol (UFC) and blood ACTH concentrations, and hypokalemia. However, for patients whose primary lesions are difficult to remove, bilateral adrenalectomy is the recommended treatment method according to guidelines. Here,
Fang Sun+6 more
wiley +1 more source
ABSTRACT Objectives To determine if the assessment of CD8+ tumor‐infiltrating lymphocytes (TILs) adds prognostic information to the PD‐L1 combined positive score (CPS) in recurrent/metastatic (R/M) head and neck squamous cell carcinoma (HNSCC). Methods A retrospective case series was performed of 77 patients with R/M HNSCC between 2003 and 2019.
Catherine T. Haring+8 more
wiley +1 more source
NEW-ONSET PRIMARY ADRENAL INSUFFICIENCY AFTER COVID-19: CASE REPORT. [PDF]
Kayhan Y+4 more
europepmc +1 more source
Abstract Background Glucagon‐like peptide 1 receptor agonists and combination medications (hereafter collectively referred to as GLP‐1s) are shifting the treatment landscape for obesity. However, real‐world challenges and limited clinician and public knowledge on nutritional and lifestyle interventions can limit GLP‐1 efficacy, equitable results, and ...
Dariush Mozaffarian+17 more
wiley +1 more source
Cortisol, Anxiety, and TNFα Mediate the Relationship Between BMI and Executive Functions
ABSTRACT Overweight and obesity are associated with poorer executive functions (EF). The underlying mechanisms contributing to this relationship are not yet conclusive, but cortisol, anxiety, and inflammation are likely among the contributing factors. Our objective was to evaluate whether fibrinogen, tumour necrosis factor alpha (TNFα), cortisol, and ...
Anna Prunell‐Castañé+6 more
wiley +1 more source
Association Between Hair Cortisol and Psychopathology in Children With a Chronic Physical Illness
ABSTRACT Children with a chronic physical illness (CPI) experience significant stress and are at a greater risk of psychopathology. However, little is known about chronic stress and its relationship with psychopathology in this population. Over the last decade, hair cortisol concentration (HCC) has emerged as a viable biomarker of chronic stress.
Emma A. L. Littler+3 more
wiley +1 more source
Subcellular distribution and arterio-venous differences of synthetic 3H-ß1-23-Corticotrophin-23-amideacetate in the adrenal of rats [PDF]
Müller, O. A., Scriba, Peter Christian
core
ABSTRACT Introduction Childhood trauma is a well‐established risk factor for major depressive disorder (MDD) and is often associated with attenuated response to conventional antidepressant therapies. Ketamine has emerged as an effective treatment for treatment‐resistant depression (TRD), but the impact of childhood trauma on its effectiveness remains ...
Danica E. Johnson+4 more
wiley +1 more source