Chronic adrenal insufficiency is caused by insufficient secretion of hormones by the adrenal cortex due to dysfunction of one or more links of the hypothalamic-pituitary-adrenal system.
V. G. Chobitko, A. P. Belova
doaj +1 more source
Adrenal crises: perspectives and research directions [PDF]
Adrenal crises (AC) are life-threatening complications of adrenal insufficiency (AI). These events have an estimated incidence of between 5 and 10 ACs/100 patient years (PY) and are responsible for some of the increased morbidity and excess mortality ...
Falhammar, H, Rushworth, R, Torpy, D
core +2 more sources
Primary adrenal lymphoma: Differential involvement with varying adrenal function
Primary adrenal Non-Hodgkin′s lymphoma is rare. The symptoms of the disease and response to treatment are variable depending on the type of lymphoma, tumor size, and presence of adrenal insufficiency.
Shiekh Aejaz Aziz +4 more
doaj +1 more source
GNAS mutation is an unusual cause of primary adrenal insufficiency: a case report
Background Primary adrenal insufficiency in children has non-specific and extensive clinical features, so the diagnosis of its etiology is complex and challenging.
Yajie Tong +3 more
doaj +1 more source
Reversible dilated cardiomyopathy as a complication of adrenal cortex insufficiency: a case report
Background Cardiovascular manifestations associated with Addison’s disease are previously documented. We described a case of an 11-year-old girl who developed dilated cardiomyopathy as a complication to Addison’s disease.
Mohammad Alkhateeb +3 more
doaj +1 more source
Primary adrenal insufficiency in adults: 150 years after Addison [PDF]
Thomas Addison first described, 150 years ago, a clinical syndrome characterized by salt-wasting and skin hyperpigmentation, associated with a destruction of the adrenal gland.
Alvarenga, Daniela B. de +7 more
core +4 more sources
A rare occurrence of central precocious puberty in adrenal hypoplasia congenita
AHC (X-linked adrenal hypoplasia congenita) is a rare cause of adrenal insufficiency due to mutations in the DAX1 gene. It traditionally causes hypogonadotropic hypogonadism.
Rajesh Joshi, Karthik Shroff
doaj +1 more source
Mutational analysis of DAX1 in patients with hypogonadotropic hypogonadism or pubertal delay [PDF]
Although delayed puberty is relatively common and often familial, its molecular and pathophysiologic basis is poorly understood. In contrast, the molecular mechanisms underlying some forms of hypogonadotropic hypogonadism (HH) are clearer, following the ...
Achermann, JC +12 more
core +1 more source
Glucocorticoid therapy for adrenal insufficiency: nonadherence, concerns and dissatisfaction with information [PDF]
Objective: Appropriate self‐management of glucocorticoid therapy (GC) is crucial for patients with adrenal insufficiency (AI). We aimed to describe patients’ self‐reported nonadherence to GC, evaluate perceived doubts about need for GC, concerns about ...
Carroll, P. +3 more
core +2 more sources
The hepatoadrenal syndrome: A common yet unrecognized clinical condition [PDF]
Objective: Adrenal failure is common in critically ill patients, particularly those with sepsis. As liver failure and sepsis are both associated with increased circulating levels of endotoxin and proinflammatory mediators and reduced levels of apoprotein-
Acton +51 more
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