Results 101 to 110 of about 54,905 (262)

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, EarlyView.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Secondary prophylaxis of variceal hemorrhage in biliary atresia—Analysis of prospective multicenter studies

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Lee M. Bass, Kieran Hawthorne, John C. Magee, Benjamin L. Shneider, Childhood Liver Disease Research Network (ChiLDReN), Lee M. Bass, Kieran Hawthorne, John C. Magee, Simon P. Horslen, Wen Ye, Jean P. Molleston, Lisa Henn, Daniel H. Leung, Ronald J. Sokol, Saul J. Karpen, Philip Rosenthal, Kathleen M. Loomes, Rohit Kohli, Pamela L. Valentino, Alexander Miethke, Vicky L. Ng, M. Kyle Jensen, Benjamin L. Shneider   +22 more
wiley   +1 more source

Advances in the Diagnosis, Treatment, and Management of Liver Nodules: A Comprehensive Review

Portal Hypertension &Cirrhosis, EarlyView.
Liver nodules commonly occur due to various causes, some of which are malignant or may undergo malignant transformation, leading to disease progression or delayed detection in clinical practice. The widespread use of imaging methods has increased the detection rate of liver nodules. Furthermore, precision medicine techniques and artificial intelligence
Chang Gao, Dongyang Chen, Youpeng Chen
wiley   +1 more source

Extrahepatic Conditions Associated With Primary Biliary Cirrhosis [PDF]

, 2009
Ricardo Moreno‐Otero, María Trapero-Marugán   +1 more
openalex   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Impact of Obesity and MASH on Zonal Hepatocellular Statin Exposure: Pharmacodynamic Insights From a Permeability‐Limited Multicompartment Liver Model

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
Obesity, MASH and Statins: Insights from a PBPK/PD Zonal Liver Model. ABSTRACT Statins are frequently prescribed for hyperlipidemia, a common comorbidity in patients with obesity and/or metabolic dysfunction‐associated steatohepatitis (MASH). However, limited knowledge exists on how MASH may alter statin disposition within hepatocytes where the statin ...
William A. Murphy, Noora Sjöstedt, Mailys De Sousa Mendes, Mattie Hartauer, Kim L. R. Brouwer, Sibylle Neuhoff   +5 more
wiley   +1 more source

Physiologically‐Based Pharmacokinetic Modeling to Support Pediatric Clinical Development: An IQ Working Group Perspective on the Current Status and Challenges

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT Pediatric extrapolation strategies issued by health authorities have streamlined pediatric drug development and reduced the unnecessary burden of conducting pediatric clinical studies. In line with these strategies, physiologically based pharmacokinetic (PBPK) models have been utilized extensively for initial dosing regimen and sampling ...
James W. T. Yates, Michael Zientek, Kunal S. Taskar, Wen Lin, Tycho Heimbach, Stefan Willmann, Jessica Rehmel, Neil Parrott, Michael Hanley, Justine Badee, Yuan Chen, Susan Cole, Loeckie De Zwart, Sebastian Haertter, Rongrong Jiang, Masakatsu Kotsuma, Guiqing Liang, Yu‐Wei Lin, Jing Liu, Ying Ou, Juliane Rascher, Naveed A. Shaik, Jan Wahlstrom, Xiaofeng Wang, Guangqing Xiao, Ka Lai Yee, S. Y. Amy Cheung   +26 more
wiley   +1 more source

Efficacy of silymarinum at chronic diffuse liver diseases

Российский журнал гастроэнтерологии, гепатологии, колопроктологии, 2011
The aim of review. To present modern data of foreign literature on efficacy of preparation of Silybum marianum – silymarinum at patients with alcoholinduced liver disease, non-alcoholic steatohepatosis and primary biliary cirrhosis.Original positions ...
A. V. Matvieiev, E. I. Konyaeva, N. V. Matvieieva   +2 more
doaj  

Hybrid laparoscopic Inokuchi shunt procedure for refractory pleural effusion and ascites associated with primary biliary cirrhosis: A case report. [PDF]

Int J Surg Case Rep, 2021
Obana A, Sato Y, Koyama M, Kitamura K, Suwa T.   +4 more
europepmc   +1 more source

Trends in Primary Biliary Cholangitis: Prospective Cohort Study From the European Reference Network Registry (R‐LIVER)

United European Gastroenterology Journal, EarlyView.
ABSTRACT Background and Aims The European Reference Network on Hepatological Diseases (ERN RARE‐LIVER) is a Europe‐wide network for centers of excellence in the management of rare liver diseases. We aimed to evaluate the current diagnostic and therapeutic trends of primary biliary cholangitis (PBC).
A. Gerussi, E. Nofit, D. P. Bernasconi, C. Kroll, F. Groß, I. Schregel, A. Marini, L. Cristoferi, F. Malinverno, M. Papp, G. Dalekos, E. Rigopoulou, M. K. Janik, P. Milkiewitz, H. Ytting, A. Leburgue, F. Braun, C. Casar, M. Sebode, A. Lohse, B. Hansen, M. Carbone, C. Schramm, P. Invernizzi   +23 more
wiley   +1 more source