Results 161 to 170 of about 11,388,967 (312)
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
Primary Care Division Operational Plan 2017
, 2017 The Primary Care chapter of the 2017 National Service Plan (NSP) sets out the key priorities and volume of primary care, social inclusion, palliative care and primary care reimbursement services (PCRS) to be provided in 2017, within the funding available.
Primary Care Division. Health Service Executive.
core
A better future through primary health care
The Lancet Primary CareThe Lancet Primary Care
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Misinformation, disinformation, and the fight for health
The Lancet Primary CareThe Lancet Primary Care
doaj +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Community research to elevate women’s health
The Lancet Primary CareThe Lancet Primary Care
doaj +1 more source
Primary Care in Indonesia [PDF]
Journal of Child Health Care, 2006 Shields, Linda, Hartati, Lucia Endang
openaire +4 more sources
Gut microbiota alterations in patients with non‐small‐cell lung cancer undergoing chemoradiotherapy
Molecular Oncology, EarlyView.We investigated the impact of concurrent chemoradiotherapy (CRT) on the gut microbiota in patients with locally advanced non‐small‐cell lung cancer. Overall gut microbiota composition remained largely stable throughout CRT while antibiotic exposure may influence microbial diversity.
Hanne Marte Nymoen +19 more
wiley +1 more source
Patient violence at the frontline of care
The Lancet Primary CareThe Lancet Primary Care
doaj +1 more source