Results 161 to 170 of about 3,564,494 (317)

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source

PEN-Plus: a first step to better care

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Implementing primary care concepts in higher education : a mixed method study in Flanders (Belgium) [PDF]

BackgroundThe policy shift towards person-centred integrated primary care systems drives interest in primary care across higher education programs. In Flanders, the Primary Care Academy (PCA) is established to support this policy shift.
De Sutter, AnGE390019833577848010009558120000-0002-2540-8307F4CC8D08-F0ED-11E1-A9DE-61C894A0A6B4, Van Landschoot, LeenGE3900199770438780200480264762B6E096-2240-11E3-BD2F-D1D610BDE39D, Van Hecke, AnnGE39UZGent0019943162598010018234550000-0003-3576-7159F702A1AC-F0ED-11E1-A9DE-61C894A0A6B4, Martin, Sandra, Verte, Emily, Pype, PeterGE390001110008378020008792010000-0003-2273-02502C9D5B40-F0EE-11E1-A9DE-61C894A0A6B4, on behalf of the Primary Care Academy, [missing], Remmen, Roy, Pless, Sam, Decat, PeterGE390001006743778020000673300000-0001-8948-6040F87ACCD0-F0ED-11E1-A9DE-61C894A0A6B4, Lahousse, LiesFW030020051517658020008488850000-0002-3494-436304778CDA-F0EE-11E1-A9DE-61C894A0A6B4, Van de Velde, DominiqueGE370001110529738020001164360000-0001-6982-1075F8A4C51C-F0ED-11E1-A9DE-61C894A0A6B4, Boeckxstaens, PaulineGE390019991117968020004338090000-0003-0445-2533FB504B4C-F0ED-11E1-A9DE-61C894A0A6B4, De Vriendt, PatriciaUGent8020013670299710692947550000-0003-4861-78386E75BC4A-342F-11E2-AB34-F0CC10BDE39D, Boeykens, DagjeGE370001200021348020033026820000-0002-4062-5748C1095AA4-F0EE-11E1-A197-91C894A0A6B4, Vanneste, LotteGE390001813420058020036402630009-0000-7976-515064B6A814-DD65-11E8-9122-D5775607D3EF, Haverals, ReiniGE390001813410928020034646530000-0002-4297-196X64B7977E-DD65-11E8-9122-D5775607D3EF, Roose, RudiPP040019861408768010010904970000-0001-7508-4593F5086116-F0ED-11E1-A9DE-61C894A0A6B4   +17 more
core  

Primary Care

Upsala Journal of Medical Sciences, 1990
openaire   +2 more sources

A better future through primary health care

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

TEP (Treatment Escalation plan) Process Maps [PDF]

TEP (Treatment Escalation plan) Process Maps CC BY-NC-ND 4.0TEP (Treatment Escalation plan) Process ...
Primary Care Team
core   +1 more source

Misinformation, disinformation, and the fight for health

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Addressing Primary Care Needs of Cancer Survivors: The Primary Care Engaged Research for Cancer Survivorship Care (PERCS) Initiative. [PDF]

Ann Fam Med
Mollica MA, O'Malley DM, Balasubramanian BA, Ferrante JM, Greiner A, Hudson SV, Klemp J, Lawrence J, Lee SC, Penedo FJ, Doose M, Fleszar-Pavlovic S, Tonorezos E.   +12 more
europepmc   +1 more source