Results 151 to 160 of about 7,840,227 (263)

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

Primary Care Academy : lessons learned from a large scale innovative primary care project

: Introduction and context: The social and healthcare system faces numerous challenges, with primary care playing a key role in achieving universal and equitable health coverage.
Vert\ue9, Emily, De Vriendt, Patricia, De Loof, Hans, Remmen, Roy, Weemaes, Isabel, Steurs, Manon, Anthierens, Sibyl   +6 more
core  

Layers of complexity: a directed content analysis of implementation determinants for integrative group medical visits for patients with chronic pain in safety-net primary care

BACKGROUND: Chronic pain impacts a quarter of U.S. adults and is pervasive among populations who rely on safety-net settings (e.g., hospital outpatient clinics and Federally Qualified Health Centers) for chronic pain management.
Gardiner, Paula, Ferriola-Bruckenstein, Kate, Tomczak, Paula, Leeman, Jennifer, Roth, Isabel J   +4 more
core   +1 more source

Misinformation, disinformation, and the fight for health

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Bridging the gap: a genetically validated avian chorioallantoic membrane platform for investigation of spontaneous circulating tumor cells

Molecular Oncology, EarlyView.
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth, Rui P. L. Neves, Julia Geheb, Christian Ballmeyer, Nathalie Gaßmann, Kiki C. Andree, Monica Sudarsanam, Christiane Driemel, Celine Örencik, Andrè Franken, Eslam Elmaghraby, Sven H. Loosen, Roderburg Christoph, Sebastian Schoelch, Hans Neubauer, Wolfram T. Knoefel, Nikolas H. Stoecklein, Georg Fluegen   +17 more
wiley   +1 more source

Patient violence at the frontline of care

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Primary Care in Indonesia [PDF]

Journal of Child Health Care, 2006
Shields, Linda, Hartati, Lucia Endang
openaire   +4 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Health Professional Underserved Areas Report, Kansas, 2012. Primary care underserved areas report, Kansas, 2012.

, 2013
INTRODUCTION -- Kansas PopulatiOn Density Peer Groups -- PART ONE: HEALTH CARE WORKFORCE SHORTAGE AREAS: Federal Primary Care HPSAs (Health Professional Shortage Areas); Federal Dental HPSAs (Health Professional Shortage Areas); Federal Mental Health ...
Kansas. Primary Care Office.
core   +1 more source

Community research to elevate women’s health

The Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source