Results 131 to 140 of about 7,840,227 (263)

Primary Care Division Operational Plan 2017

open access: yes, 2017
The Primary Care chapter of the 2017 National Service Plan (NSP) sets out the key priorities and volume of primary care, social inclusion, palliative care and primary care reimbursement services (PCRS) to be provided in 2017, within the funding available.
Primary Care Division. Health Service Executive.
core  

A review of certain recent advances in primary health care [PDF]

open access: yes, 2014
A strong primary health care system is the keystone of health care and helps patients manage their health conditions in the community, whilst also providing disease prevention services.
Sammut, Mario R.   +3 more
core  

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Implementing screening programmes in primary care versus a centralised administration: a qualitative study of atrial fibrillation screening

open access: yesBMC Primary Care
Background General practices have been tasked with increasing detection of atrial fibrillation (AF) to reduce stroke. Paroxysmal AF is often missed through usual care but can be detected through screening with repeated ECGs over a period of time using ...
Rakesh N Modi   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

What makes Care Plus effective in a provincial Primary Health Organisation? Perceptions of primary care workers.

open access: yes, 2009
INTRODUCTION: Care Plus is a New Zealand chronic care initiative. It provides funding for extra primary care visits for patients with chronic diseases and aims to improve chronic care management, primary health care team work and reduce inequalities in ...
Eggleton, Kyle, Kenealy, Timothy
core  

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

open access: yesMolecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou   +4 more
wiley   +1 more source

Moving care into the community

open access: yesThe Lancet Primary Care
The Lancet Primary Care
doaj   +1 more source

Primary Care

open access: yesUpsala Journal of Medical Sciences, 1990
openaire   +2 more sources

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