Results 111 to 120 of about 7,840,227 (263)
Men and their health: a primary care initiative: Part 1. Health status, attitudes and behavioural patterns of middle aged men in a general practice in an urban area of Dublin. Part 2. Stress and anger management in middle aged men in primary care. [PDF]
, 2004 I am pleased to welcome this report on men's health in primary care, which is both inform· ative and innovative. The study confirms that men are interested in their health but that barriers do exist in terms of attitudes and access.
O'Dowd, Tom, O'Keefe, Frances
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Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Co-designing of Patient Safety Incident Disclosure Process in Primary Healthcare System in Qatar
Patient Experience JournalThe importance of disclosing a patient safety incident to the patient involved is recognized. In Qatar, there is no legal requirement for disclosure. The primary health care system in Qatar includes 30 health centers located around the country, managed ...
Nawal Khattabi +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
Molecular Oncology, EarlyView.The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington +10 more
wiley +1 more source
Primary care division: operational plan 2014 [PDF]
, 2013 The development of the Primary Care service is a key element of the overall Health Reform programme. The core objective is to achieve a more balanced health service by ensuring that the vast majority of patients and clients who require urgent or ...
Health Service Executive (HSE), Primary Care Division
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Analysing sub-acute and primary health care interfaces – research in the elderly
, 2015 The National Health and Hospital Reform Commission (NHHRC)1 recommended major changes to the way services are delivered to ensure people with complex needs get appropriate and timely care in the most appropriate setting.
Quigley, Rachel +4 more
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