Determinants of frailty in primary care patients with COPD: the Greek UNLOCK study
BMC Pulmonary Medicine, 2019 Background Frailty is a state of increased vulnerability that has a significant risk of unfavorable outcomes such as increased dependency and/or death, but little is known about frailty in people with chronic obstructive pulmonary disease (COPD).
Despo Ierodiakonou +15 more
doaj +1 more source
Incremental Cost Estimates for the Patient-Centered Medical Home [PDF]
, 2009 Based on data from thirty-five primary care practices, analyzes the costs associated with the medical home model, in which primary care practices also provide care coordination, patient education, and related services.
Aimee Williams +7 more
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Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Confidence of primary care physicians in their ability to carry out basic medical genetic tasks—a European survey in five countries—Part 1 [PDF]
, 2010 Irmgard Nippert +10 more
openalex +1 more source
Regional and Racial Variation in Primary Care and the Quality of Care Among Medicare Beneficiaries [PDF]
, 2010 Analyzes links between access to and use of primary care, clinician supply, and disparities in diabetes-related leg amputation, hospitalization, and mammography rates.
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Understanding the Paramedic's Role in Primary Care: A Realistic Review
, 2023 Retracted
openalex +1 more source
Eliminating Geographic Disparities in Primary-Care Services [PDF]
, 2006 This fact sheet describes the risks associated with the lack of primary care, and how we can improve the health of all families by increasing access to such care.
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