Results 101 to 110 of about 3,564,494 (317)

Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean, Lara V. Graham, Christina Putnam, Rosa Gomes Alves Martins, Daniel T. Harding, Tim J. Underwood, Zoë S. Walters, Matthew D. Blunt   +7 more
wiley   +1 more source

Principles and practice of primary health care integration: Learning and up-scaling results from a regional GP Superclinic [PDF]

, 2015
There is no clear understanding of what ‘good’ integration looks like. Existing models of integration focus on integration around the clinician, the service and the health system, but largely ignore the patient.
Chamberlain, Daniel, Hill, Peter, Barlow, Kegan, Avila, Catharine, Keast, Robyn, Nancarrow, Susan Alison, Doran, Frances, Bradbury, Joanne   +7 more
core  

Development and Implementation of a Disease‐Targeted Storybook as a Clinical Tool for Children With Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Although significant progress has been made in childhood leukemia survival, healthcare providers, and caregivers often face challenges in explaining this disease to patients. Disease‐targeted storybooks have been proposed as a tool to facilitate the understanding of diagnoses and treatment.
Nutvipha Ummartyotin, Usanarat Anurathapan, Rawiwan Roongpraiwan, Potchanee Dandamrongrak, Siriporn Nakhonchai, Pawin Numthavaj, Vilawan Chirdkiatgumchai   +6 more
wiley   +1 more source

On Hierarchical Composite Endpoints in Pediatric Cancer Supportive Care: Illustrative Examples From Two Multi‐Center Phase‐III Randomized Clinical Trials

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric supportive care clinical trials often involve multiple clinically important outcomes, complicating trial interpretation. Hierarchical composite endpoints (HCEs) provide a framework to integrate key outcomes according to clinical importance.
Willem H. Collier, Mark Zobeck, Adam J. Esbenshade, Christopher C. Dvorak, Lillian Sung, David Freyer, Sarah Alexander, Etan Orgel, Nicole J. Ullrich, Zach Prudowsky, Brian Fisher, Caitlin W. Elgarten   +11 more
wiley   +1 more source

Determinants of frailty in primary care patients with COPD: the Greek UNLOCK study

BMC Pulmonary Medicine, 2019
Background Frailty is a state of increased vulnerability that has a significant risk of unfavorable outcomes such as increased dependency and/or death, but little is known about frailty in people with chronic obstructive pulmonary disease (COPD).
Despo Ierodiakonou, Maria Kampouraki, Ioannis Poulonirakis, Polyvios Papadokostakis, Eleftheria Lintovoi, Dimitris Karanassos, Kyriakos Maltezis, Maria Chorti, Evangelos Petrovitsos, Sofia Dimopoulou, Sam Hamind, Ioannis Gialamas, Polyxeni Athanasiou, Vasiliki Bempi, Irene Lambraki, Ioanna Tsiligianni   +15 more
doaj   +1 more source

The Role of Chemotherapy in Pediatric Myoepithelial Carcinoma: A Systematic Review of the Literature

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Myoepithelial carcinoma (MEC) in pediatric patients is a rare and aggressive malignancy characterized by heterogeneous morphology and variable molecular features. The optimal role of chemotherapy remains unclear. We conducted a systematic review according to PRISMA 2020 guidelines to evaluate chemotherapy in pediatric and young‐adult patients ...
Marco Salvi, Maria Carmen Affinita, Giulia Fichera, Luisa Santoro, Angela Scagnellato, Calogero Virgone, Elena Poli, Gianni Bisogno   +7 more
wiley   +1 more source

A review of certain recent advances in primary health care [PDF]

, 2014
A strong primary health care system is the keystone of health care and helps patients manage their health conditions in the community, whilst also providing disease prevention services.
Sammut, Mario R., Bezzina, Glorianne, Baldacchino, Marilyn, Scerri, Anne Marie   +3 more
core  

Comparing quality of public primary care between Hong Kong and Shanghai using validated patient assessment tools. [PDF]

, 2015
OBJECTIVES: Primary care is the key element of health reform in China. The objective of this study was to compare patient assessed quality of public primary care between Hong Kong, a city with established primary care environment influenced by its ...
Xu, Jianguang, Samuel Y S Wong, Sian M. Griffiths (115751), Donald Li, Donald Li (715412), Shi, Leiyu, Griffiths Sian M., Wei Xiaolin, Yang Nan, Wong Samuel Y. S., Li Haitao, Yang, Nan, Leiyu Shi, Shi Leiyu, Jinling Tang (166283), Li, Donald, Samuel Y. S. Wong (305077), Owolabi Onikepe, Nan Yang, Jianguang Xu (715411), Leiyu Shi (705227), Wei, Xiaolin, Tang Jinling, Jianguang Xu, Xu Jianguang, Tang, Jinling, Onikepe Owolabi (715410), Jinling Tang, Owolabi, Onikepe, Haitao Li, Onikepe Owolabi, Xiaolin Wei (287892), Xiaolin Wei, Li Donald, Wong, Samuel YS, Nan Yang (305078), Haitao Li (305080), Li, Haitao, Sian M Griffiths, Griffiths, Sian M   +39 more
core   +1 more source

Determining Parental Factors for Clinical Trial Attrition in Pediatric Acute Lymphoblastic Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Despite high enrollment rates on Children's Oncology Group (COG) protocols, attrition after initial consent is challenging, introducing bias and prolonging trial completion. While adult oncology literature has identified predictors of withdrawal, little is known about caregiver decision‐making for child participation in ...
Kimberly L. Stathas, Jakob Q. Weiss, Kellee N. Parker, Cathy Lee‐Miller   +3 more
wiley   +1 more source

Health Risk Screening and Counselling of Adolescents in Primary Care: a Cluster Randomised Controlled Trial [PDF]

, 2007
The research reported in this paper is a project of the Australian Primary Health Care Research Institute which is supported by a grant from the Australian Government Department of Health and Ageing under the Primary Health Care Research Evaluation and ...
Chondros, P, The PARTY Team, Sanci, L, Sawyer, S, Patton, G   +4 more
core