Results 121 to 130 of about 7,840,227 (263)
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
, 2015 The research reported in this paper is a project of the Australian Primary Health Care Research Institute which is supported by a grant from the Australian Government Department of Health and Ageing under the Primary Health Care Research Evaluation and ...
core
The Contribution of consumer health organisations to chronic disease self management in the context of primary care. [PDF]
, 2007 This project aims to answer the question, what are the current and potential contributions of chronic illness-focused self-help organisations in the integrated delivery of primary health care?The research reported in this paper is a project of the ...
Mutch, Allyson +4 more
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Assessing social determinants of health in primary care: Liability or opportunity
, 2019 Health care is never boring. It changes rapidly based on political winds, financial models, novel terminology, and biomedical advances. In the past decade, there has been large-scale implementation of integrated health care, routine screening for common ...
Runyan, Christine
core +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
, 2015 There is no clear understanding of what ‘good’ integration looks like. Existing models of integration focus on integration around the clinician, the service and the health system, but largely ignore the patient.
Chamberlain, Daniel +7 more
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REDIRECT: reducing older patients' avoidable presentations for emergency care treatment [PDF]
, 2015 The project brings together researchers, primary and acute care service providers, and consumers with the primary aim of identifying strategies to reduce avoidable presentations of older patients to Emergency Departments (ED) by redirecting them to ...
Biezen, Ruby +9 more
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Chronic Episodic Hypotension as a Cause of Chronic Kidney Disease
Case Reports in MedicineChronic kidney disease (CKD) is a global health concern characterized by the gradual loss of renal function as seen by the decline of the estimated glomerular filtration rate (eGFR). While hypertension is a well-documented risk factor for CKD progression,
Hong Phuc Nguyen +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source