Results 171 to 180 of about 6,056,808 (246)

Optimizing AI solutions for population health in primary care. [PDF]

NPJ Digit Med
Basu S, Bermudez-Canete P, Hall TC, Rajpurkar P.   +3 more
europepmc   +1 more source

Short peptide perturbs spermatogenesis via immune microenvironment dysregulation and mitochondrial imbalance

FEBS Open Bio, EarlyView.
In the blood–testis barrier, occludin is crucial for tight junctions. This study demonstrates that occludin‐targeting short peptides disrupt junction integrity, inducing immune cell infiltration, tumor necrosis factor‐α/interleukin‐6 secretion and mitochondrial dysfunction, ultimately triggering apoptosis.
Heng Wang, Xiaofang Tan, Deyu Chen
wiley   +1 more source

Improving Outcomes in Survivors of Sepsis-The Transition from Secondary to Primary Care, and the Role of Primary Care: A Narrative Review. [PDF]

J Clin Med
Taylor R, Vollam S, McKechnie SR, Shah A.   +3 more
europepmc   +1 more source

Earthing effects on mitochondrial function: ATP production and ROS generation

FEBS Open Bio, EarlyView.
In contrast to sham and naive controls, grounded mitochondria not only exhibit significantly enhanced energy production but also demonstrate a remarkable reduction in membrane potential and oxidative stress. This suggests a profound improvement in mitochondrial health, presenting a promising avenue for therapeutic interventions.
Cecilia Giulivi, Richard Kotz
wiley   +1 more source

Primary care in the United kingdom. [PDF]

, 2008
Majeed, Azeem, Molokhia, Mariam
core   +1 more source

Enhancing early detection of cognitive impairment in primary care with the TabCAT-BHA. [PDF]

Alzheimers Dement
Breithaupt AG, Sideman AB, Goode C, Hill-Sakurai L, Premkumar M, Scheffler AW, Chodos A, Tsoy E, Rankin KP, Kramer JH, Bui N, Jarrott S, Gaynor L, Chang OLB, Chow C, Kahn JG, Possin KL.   +16 more
europepmc   +1 more source

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

What do Primary Care Patients Want? [PDF]

Ann Fam Med
Johansen ME.
europepmc   +1 more source

Preparation and characterization of renal cell peptides from fetal rats for their antitumor activity

FEBS Open Bio, EarlyView.
This study aimed to prepare renal cells (RCs) from fetal rats which were digested by enzymes. Candidate peptides RCPs were characterized by capillary HPLC and MS and their bioactivity was predicted using peptideranker. The predicted top 10 bioactive peptides were synthesized.
Zhe Zhang, Yuan Cao, Jing Du, Ying Zhang, Junxia Wang, Ying Yuan, Lianqing Sun   +6 more
wiley   +1 more source

Neighborhood Determinants of Primary Care Access in Virginia. [PDF]

Ann Fam Med
Shadowen HM, Gilbert JL, Webel B, Funk A, Lee JH, Strayer SM, Sabo RT, Walker LS, Topmiller M, Mitchell A, Britz JB, Barnes AJ, Krist AH.   +12 more
europepmc   +1 more source