Results 71 to 80 of about 11,134,118 (343)

Primary care trusts [PDF]

BMJ, 2004
Just over two years ago, in a reorganisation of the NHS in England, 303 primary care trusts were created, each with responsibility for providing primary health care, improving health, and commissioning secondary care services for a population of around 180 000.
Nicholas Mays, David J. Hunter, Judith Smith, Jennifer Dixon, Nigel Edwards, Ray Robinson, Charles Normand, Kieran Walshe   +7 more
openaire   +4 more sources

Standards of Medical Care in Diabetes—2020 Abridged for Primary Care Providers

Clinical Diabetes, 2019
The American Diabetes Association’s (ADA’s) Standards of Medical Care in Diabetes is updated and published annually in a supplement to the January issue ofDiabetes Care.
M. Riddle, Reinhard W. Holl
semanticscholar   +1 more source

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

When investigating depression and anxiety in undergraduate medical students timing of assessment is an important factor - a multicentre cross-sectional study

BMC Medical Education, 2020
Background Symptoms of depression and anxiety experienced by undergraduate medical students have become a prominent concern. Evidence about students’ depression and anxiety including prevalence, trajectory during medical education, gender differences and
Pia Thiemann, James Brimicombe, John Benson, Thelma Quince   +3 more
doaj   +1 more source

Acceptability, benefits, and challenges of video consulting: a qualitative study in primary care

The British journal of general practice : the journal of the Royal College of General Practitioners, 2019
Background People increasingly communicate online, using visual communication mediums such as Skype and FaceTime. Growing demands on primary care services mean that new ways of providing patient care are being considered. Video consultation (VC) over the
E. Donaghy, H. Atherton, V. Hammersley, Hannah McNeilly, A. Bikker, L. Robbins, John L Campbell, B. McKinstry   +7 more
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

FEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere, Claudio Silva De Freitas, Adam Bates, Kenneth B. Storey, Pedro Beltran‐Alvarez, Katharina C. Wollenberg Valero   +5 more
wiley   +1 more source

Optimal primary care management of clinical osteoarthritis and joint pain in older people: a mixed-methods programme of systematic reviews, observational and qualitative studies, and randomised controlled trials

Programme Grants for Applied Research, 2018
Background: Osteoarthritis (OA) is the most common long-term condition managed in UK general practice. However, care is suboptimal despite evidence that primary care and community-based interventions can reduce OA pain and disability.
Elaine Hay, Krysia Dziedzic, Nadine Foster, George Peat, Danielle van der Windt, Bernadette Bartlam, Milisa Blagojevic-Bucknall, John Edwards, Emma Healey, Melanie Holden, Rhian Hughes, Clare Jinks, Kelvin Jordan, Sue Jowett, Martyn Lewis, Christian Mallen, Andrew Morden, Elaine Nicholls, Bie Nio Ong, Mark Porcheret, Jerome Wulff, Jesse Kigozi, Raymond Oppong, Zoe Paskins, Peter Croft   +24 more
doaj   +1 more source

Prevalence of children born small for gestational age with short stature who qualify for growth hormone treatment

Italian Journal of Pediatrics, 2021
Background Recombinant human growth hormone (rhGH) is approved in Europe as a treatment for short children born small for gestational age (SGA) since 2003. However, no study evaluated the prevalence of SGA children with short stature who qualify for rhGH
Gianluca Tamaro, Mariagrazia Pizzul, Giuliana Gaeta, Raffaella Servello, Marina Trevisan, Patricia Böhm, Paola Manera Ada Materassi, Anna Macaluso, Denis Valentini, Maria Chiara Pellegrin, Egidio Barbi, Gianluca Tornese   +11 more
doaj   +1 more source

Effectiveness of brief alcohol interventions in primary care populations.

Cochrane Database of Systematic Reviews, 2018
BACKGROUND Excessive drinking is a significant cause of mortality, morbidity and social problems in many countries. Brief interventions aim to reduce alcohol consumption and related harm in hazardous and harmful drinkers who are not actively seeking help
E. Kaner, F. Beyer, C. Muirhead, F. Campbell, E. Pienaar, N. Bertholet, J. Daeppen, J. Saunders, B. Burnand   +8 more
semanticscholar   +1 more source

Protonophore activity of short‐chain fatty acids induces their intracellular accumulation and acidification

FEBS Letters, EarlyView.
The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang, Frans Bianchi, Geert van den Bogaart   +2 more
wiley   +1 more source