Results 251 to 260 of about 25,833,379 (292)

Modified Newcastle Regimen Improves Survival Despite Central Nervous System Relapse in Monomorphic Epitheliotropic Intestinal T‐Cell Lymphoma

eJHaem, Volume 7, Issue 5, October 2026.
ABSTRACT Background Monomorphic epitheliotropic intestinal T‐cell lymphoma (MEITL) is a rare, aggressive malignancy with a median overall survival (OS) of 7–15 months. The Newcastle regimen, comprising cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP), ifosfamide, etoposide, and epirubicin (IVE), and intermediate‐dose methotrexate for ...
Minseung Suh, Hyungwoo Cho, Heounjeong Go, Jin‐Sook Ryu, Shin Kim, Kyoungmin Lee, Eun Jin Chae, Chan‐Sik Park, In Hye Song, Kyung Won Kim, Seok‐Byung Lim, In Ja Park, Chan Wook Kim, Yong Sik Yoon, Jaewon Hyung, Dok Hyun Yoon   +15 more
wiley   +1 more source

Multiple primary central nervous system lymphoma in the ventricular system and interpeduncular cistern: A case report. [PDF]

Oncol Lett
Ouyang Q, Sun B, Sun H, Luo J, Xu Z, Ma Y.   +5 more
europepmc   +1 more source

Harnessing Natural Killer Cells: From Neuroimmunology to Novel Therapies for Central Nervous System Diseases

MedComm, Volume 7, Issue 10, October 2026.
This review delineates the multifaceted roles of natural killer (NK) cells in the central nervous system, spanning direct cytolysis, immunoregulation, and crosstalk with the brain microenvironment. We evaluate the translational potential and challenges of NK cell immunotherapies for a spectrum of neurological conditions.
Kaihang Deng, Wai Po Chong
wiley   +1 more source

Mucosal‐Associated Invariant T Cells in Health and Disease

MedComm, Volume 7, Issue 10, October 2026.
The roles of MAIT cells in health and disease and their therapeutic applications. In healthy individuals, riboflavin metabolites secreted by commensal bacteria at mucosal sites are presented by MR1, leading to the activation of MAIT cells. Activated MAIT cells can maintain the barrier integrity of mucosal tissues in a steady state or migrate to the ...
Yu Zhao, Feng‐Mi Ou, Dan Liang, Yang Gao, Qing‐Qing Li, Yi‐Qun Kuang   +5 more
wiley   +1 more source

Composite lymphoma comprising adult T-cell leukemia/lymphoma and Epstein-Barr virus-positive primary central nervous system lymphoma. [PDF]

J Clin Exp Hematop
Toyama K, Yoshida G, Sugisaki M, Takei H, Yoshida T.   +4 more
europepmc   +1 more source

Hippo Pathway–YAP/TAZ Signaling: Molecular Mechanisms, Biological Function, Diseases, and Therapeutic Targets

MedComm, Volume 7, Issue 10, October 2026.
The Hippo–YAP/TAZ–TEAD pathway integrates mechanical and biochemical cues to govern organ growth, regeneration, cancer, and fibrosis. This review dissects pathway physiology, TEAD structural pharmacology and ligandable pockets, and therapeutic strategies spanning palmitoylation‐pocket inhibitors, PROTAC degraders, and gene/RNA therapies, highlighting ...
Xiaodan Qu, Zhan‐you Wang
wiley   +1 more source

Treatment initiation by positive liquid biopsy alone in primary central nervous system lymphoma: A retrospective analysis of a multi-institutional study. [PDF]

Neurooncol Adv
Mitobe M, Shibuma S, Takahashi H, On J, Takino T, Kawabe K, Mouri Y, Kumagai S, Kozakai T, Momoi A, Suzuki N, Fukushima T, Suzuki T, Kuroda H, Saji E, Nakamura K, Hashidate H, Nakahara A, Tomita T, Watanabe J, Tsukamoto Y, Okada M, Hiraishi T, Yamashita S, Akai T, Kuroda S, Kakita A, Sone H, Takizawa J, Oishi M, Natsumeda M.   +30 more
europepmc   +1 more source

Radiotherapy‐Induced Side Effects: Epidemiology, Pathogenesis, Prevention and Treatments

MedComm, Volume 7, Issue 10, October 2026.
Radiotherapy for malignancies frequently injures the organs’ systems through oxidative stress, fibrosis, inflammation, and vascular damage. This review systematically maps the epidemiology, pathogenesis, and emerging therapies to propose a mechanism‑network‑targeted framework for integrated, personalized care in radiation oncology.
Xiaowen Ma, Xiaoxuan Zhang, Pujun Zhao, Jiaxin Yang, Zhihao Li, Xiaoyang Han, Yixuan Wang, Zhenzhen Cui, Nian Liu, Min Li   +9 more
wiley   +1 more source

A Durable Remission Following Pseudo-Progression in Tirabrutinib Treatment for Relapsed Primary Central Nervous System Lymphoma: A Case Study. [PDF]

Case Rep Hematol
Okawara S, Ide S, Morimoto H, Tsukada J.
europepmc   +1 more source

Successful combined treatment for primary central nervous system lymphoma with massive hemorrhage: Illustrative case. [PDF]

Surg Neurol Int
Kobayashi Y, Miki Y, Tanioka D, Sakuragi Y, Terajima A, Sato Y, Kera H, Murakami K, Morofuji Y.   +8 more
europepmc   +1 more source