Results 51 to 60 of about 9,533 (204)

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source

Primary ciliary dyskinesia (Pcd) in Austria [PDF]

, 2009
Primary ciliary dyskinesia (PCD) is a rare hereditary recessive disease with symptoms of recurrent pneumonia, chronic bronchitis, bronchiectasis, and chronic sinusitis.
STRIPPOLI MP, KUEHNI CE, LESIC I, FRISCHER T, MAURER E, BARBATO, ANGELO, ERS TASKFORCE ON PRIMARY CILIARY DYSKINESIA IN CHILDREN   +6 more
core  

Primary ciliary dyskinesia in the genomics age [PDF]

, 2020
Primary ciliary dyskinesia is a genetically and clinically heterogeneous syndrome. Impaired function of motile cilia causes failure of mucociliary clearance. Patients typically present with neonatal respiratory distress of unknown cause and then continue
Omran, Heymut, Davis, Stephanie D., Lucas, Jane S., Shoemark, Amelia; id_orcid, Lucas, Jane, Shoemark, Amelia   +5 more
core   +1 more source

Testicular histopathology and its association with germ cell numbers, serum concentrations of reproductive hormones, and semen quality

Andrology, EarlyView.
Abstract Background It is well‐established that spermatogenesis, semen quality, and reproductive hormones are interlinked. It is, however, less well‐described how various specific testicular histopathologies are linked to reproductive hormones and semen quality.
Gülizar Saritas, Nina Mørup, Trine H. Johannsen, Anders Juul, Lise Aksglaede, Sofia B. Winge, Kristian Almstrup   +6 more
wiley   +1 more source

Cost-effectiveness analysis of three algorithms for diagnosing primary ciliary dyskinesia: a simulation study [PDF]

, 2019
Background: Primary Ciliary Dyskinesia (PCD) diagnosis relies on a combination of tests which may include (a) nasal Nitric Oxide (nNO), (b) High Speed Video Microscopy (HSVM) and (c) Transmission Electron Microscopy (TEM).
Kouis, Panayiotis, Middleton, Nicos, Cohen, Joshua T., Yiallouros, Panayiotis K., Papatheodorou, Stefania, Papatheodorou, Stefania I., Giallouros, George, Kyriacou, Kyriacos, Evans, John S.   +8 more
core   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Biallelic Truncating Variant in LRGUK Is Associated With Severe Multiple Morphological Abnormalities of the Sperm Flagella and Sperm Nuclear Defects in Humans

Clinical Genetics, EarlyView.
A homozygous truncating variant in LRGUK results in loss of the LRGUK protein and causes multiple morphological abnormalities of the flagella (MMAF), disrupted axonemal architecture, central pair defects, abnormal chromatin organization, and severe male infertility, establishing LRGUK as a novel human infertility gene.
Wiâme Mokkedem, Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Célia Tebbakh, Nicolas Thierry‐Mieg, Marie Bidart, Antonella Migliaccio, Rosanna Chianese, Christophe Arnoult, Raoudha Zouari, Zine‐Eddine Kherraf, Pierre F. Ray, Guillaume Martinez, Charles Coutton   +14 more
wiley   +1 more source

Factors influencing age at diagnosis of primary ciliary dyskinesia in European children.ERS Task Force on Primary Ciliary Dyskinesia in Children. [PDF]

, 2010
Primary ciliary dyskinesia (PCD) is a hereditary disorder of mucociliary clearance causing chronic upper and lower airways disease. We determined the number of patients with diagnosed PCD across Europe, described age at diagnosis and determined risk ...
Strippoli MP, Omran H, Nielsen KG, O'Callaghan C, BARBATO, ANGELO, Bush A, Lucas JS, ERS Task Force on Primary Ciliary Dyskinesia in Children, Snijders D, Frischer T, Maurer E, Yiallouros P, Kuehni CE, Eber E, Escribano A   +14 more
core  

Primary ciliary dyskinesia: improving the diagnostic approach [PDF]

, 2009
The diagnosis of primary ciliary dyskinesia (PCD) has relied on analysis of ciliary motility and ultrastructure; however, these tests are not readily available and have not been standardized. Consequently, the diagnosis of PCD may be delayed or missed or
Leigh, Margaret W, Zariwala, Maimoona A, Knowles, Michael R   +2 more
core   +2 more sources

A Novel Device to Improve the Tolerability of Intranasal Corticosteroid Sprays for Allergic Rhinitis and Postoperative Chronic Rhinosinusitis: A Crossover Trial

Clinical Otolaryngology, EarlyView.
ABSTRACT Background Allergic rhinitis (AR) and chronic rhinosinusitis (CRS) are commonly treated with intranasal corticosteroid sprays. Despite their efficacy, unpleasant sensations associated with their application, including post‐nasal drip and nasal irritation, are often cited as reasons for poor compliance.
Sethmi Ranasinghe, Xenia Berger, Wandia Kimita, Kristi Biswas, Raymond Kim, Richard Douglas   +5 more
wiley   +1 more source