Results 241 to 250 of about 20,808 (274)

Maternal Identity Among Mothers Who Survived Near‐Lethal Violence

Journal of Marriage and Family, EarlyView.
ABSTRACT Objective This study explores how mothers reconstructed their identity after surviving an attempted intimate partner homicide (IPH), in cases where their children were either directly or indirectly impacted by the violence. Background Although growing research has addressed risk factors and relationship dynamics preceding IPH, limited ...
Hila Avieli
wiley   +1 more source

Primary Cilium in Neural Crest Cells Crucial for Anterior Segment Development and Corneal Avascularity. [PDF]

Invest Ophthalmol Vis Sci
Seo S, Sonn SK, Kweon HY, Jin J, Kume T, Ko JY, Park JH, Oh GT.   +7 more
europepmc   +1 more source

A cell-autonomous role for primary cilium-mediated signaling in long-range commissural axon guidance.

Development
Dumoulin A, Wilson NH, Tucker KL, Stoeckli ET.   +3 more
europepmc   +1 more source

Ccdc66 regulates primary cilium stability, disassembly and signaling important for epithelial organization

Deretic J, Cengiz-Emek S, Seyrek E, Firat-Karalar EN.   +3 more
europepmc   +1 more source

The CPLANE protein Fuzzy regulates ciliogenesis by suppressing actin polymerization at the base of the primary cilium via p190A RhoGAP.

Development
Sharma R, Kalot R, Levin Y, Babayeva S, Kachurina N, Chung CF, Liu KJ, Bouchard M, Torban E.   +8 more
europepmc   +1 more source

Primary Cilium in Cancer Hallmarks

International Journal of Molecular Sciences, 2019
The primary cilium is a solitary, nonmotile and transitory appendage that is present in virtually all mammalian cells. Our knowledge of its ultrastructure and function is the result of more than fifty years of research that has dramatically changed our perspectives on the primary cilium.
Lucilla Fabbri, Frédéric Bost, Nathalie M Mazure   +2 more
exaly   +5 more sources

The primary cilium [PDF]

Organogenesis, 2014
The primary cilium is an antenna-like organelle that plays a vital role in organ generation and maintenance. It protrudes from the cell surface where it receives signals from the surrounding environment and relays them into the cell. These signals are then integrated to give the required outputs in terms of proliferation, differentiation, migration and
Andrew M Fry, Richard Bayliss
exaly   +3 more sources

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The role of the primary cilium in cancer

Neoplasma, 2021
As a common lethal disease, cancer is now responsible for the majority of deaths worldwide and has been the single most important barrier to increasing life expectancy in the world. The pathogenesis of cancer has been the key point of cancer therapeutics research.
Hong-Tai, Cao, Miao-Miao, Liu, Quan-Nian, Shao, Zuo-Yi, Jiao   +3 more
openaire   +2 more sources

The primary cilium undergoes dynamic size modifications during adipocyte differentiation of human adipose stem cells

Biochemical and Biophysical Research Communications, 2015
International audienceThe primary cilium is an organelle present in most of the cells of the organism. Ciliopathies are genetic disorders of the primary cilium and can be associated with obesity.
Nicolas Forcioli-Conti, Sandra Lacas-Gervais, Christian Dani   +2 more
exaly   +1 more source

A PHYSIOLOGICAL VIEW OF THE PRIMARY CILIUM

Annual Review of Physiology, 2005
▪ Abstract  The primary cilium, an organelle largely ignored by physiologists, functions both as a mechano-sensor and a chemo-sensor in renal tubular epithelia. This forgotten structure is critically involved in the determination of left-right sidedness during development and is a key factor in the development of polycystic kidney disease, as well as ...
Prætorius, Helle A., Spring, Kenneth R.
openaire   +3 more sources