Results 71 to 80 of about 4,977,244 (269)

How Do People Living With HIV (PLHIV) and AIDS Feel About the Quality of Care They Received Amid the COVID-19 Pandemic in Lagos, Nigeria?

Journal of the International Association of Providers of AIDS Care, 2023
Background: This study aimed to assess the perception of quality of care among people living with HIV (PLHIV) in Lagos, Nigeria, and identify factors influencing their perceptions. Methodology: The study was a descriptive cross-sectional survey conducted
Adeyinka Adeniran FMCPH, Yeside Shogbamimu FMCPH, Omobola Y. Ojo FMCPH, Florence C. Chieme MPH, Helen O. Olowofeso MSPH, Imane Sidebe MSc, Oladipupo Fisher MPH, Monsurat Adeleke MPH   +7 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Research needs for an improved primary care response to chronic non-communicable diseases in Africa. [PDF]

, 2010
With non-communicable diseases (NCDs) projected to become leading causes of morbidity and mortality in developing countries, research is needed to improve the primary care response, especially in sub-Saharan Africa.
Harries, AD, Grosskurth, H, J. Sekajugo, A. D. Harries, H. Grosskurth, Maher, D, Sekajugo, J, D. Maher   +7 more
core   +1 more source

A Generalized Distributed Energy Dispatch and Congestion Management Approach Applied to German and Japanese Grid Systems

IEEE Access
The growing penetration of renewable energy sources and the increasing number of electrical consumers at the low-voltage level present significant challenges for controlling the low-voltage grid.
Maximilian Kilthau, Toko Mannari, Tomo Tadokoro, Hiroyuki Hatta, Alexander Fay, Felix Gehlhoff   +5 more
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

Distributed Primary Frequency Control through Multi-Terminal HVDC Transmission Systems

, 2015
This paper presents a decentralized controller for sharing primary AC frequency control reserves through a multi-terminal HVDC grid. By using passivity arguments, the proposed controller is shown to stabilize the closed-loop system consisting of the ...
Dimarogonas, Dimos V,, Dimarogonas, Dimos V, Karl H. Johansson, Roger Wiget, Andreasson, Martin,, Martin Andreasson, Johansson, Karl H., Dimos V. Dimarogonas, Wiget, Roger,, Andreasson, Martin, Andersson, Göran, Andersson, Göran,, Wiget, Roger, Goran Andersson, Johansson, Karl H.,   +14 more
core   +1 more source

How to improve drug dosing for patients with renal impairment in primary care - a cluster-randomized controlled trial [PDF]

, 2012
Background: Patients with chronic kidney disease (CKD) are at increased risk for inappropriate or potentially harmful prescribing. The aim of this study was to examine whether a multifaceted intervention including the use of a software programme for the ...
Gerlach, Ferdinand M., Beyer, Martin, Justine Rochon, Kristina Saal, Haefeli, Walter E., Ferdinand M Gerlach, Erler, Antje, Thomas Rath, Walter E Haefeli, Petersen, Juliana, Rochon, Justine, Rath, Thomas, Saal, Kristina, Martin Beyer, Antje Erler, Juliana J Petersen   +15 more
core   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Ebola virus disease in the eyes of a rural, agrarian community in Western Nigeria: a mixed method study

BMC Public Health, 2020
Background Ebola virus disease (EVD) is a severe hemorrhagic disease caused by Ebola virus. Several outbreaks have been reported in Africa and often originated from remote agrarian communities where there are enormous misconceptions of the disease ...
Abiodun Benjamin Idowu, Ifeoma Peace Okafor, Ezekiel Sofela Oridota, Tochi Joy Okwor   +3 more
doaj   +1 more source