Results 81 to 90 of about 4,977,244 (269)

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

FEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

Glycemic control and health-related quality of life among older home-dwelling primary care patients with diabetes [PDF]

, 2017
Aims: To evaluate the health-related quality of life (HRQoL) and functional capacity in relation to glycemic control among older home-dwelling primary care patients.
Anna-Kaisa Aro, Merja Karjalainen, Mäntyselkä, Pekka, Maija Haanpää, Kautiainen, Hannu, Saltevo, Juha, Miia Tiihonen, Aro, Anna-Kaisa, Tiihonen, Miia, Juha Saltevo, Hannu Kautiainen, Pekka Mäntyselkä, Karjalainen, Merja, Haanpää, Maija   +13 more
core   +1 more source

A disease state approach to the pharmacological management of Type 2 diabetes in primary care : A position statement by Primary Care Diabetes Europe

, 2021
Type 2 diabetes and its associated comorbidities are growing more prevalent, and the complexity of optimising glycaemic control is increasing, especially on the frontlines of patient care. In many countries, most patients with type 2 diabetes are managed
Cos, X.,, Neijens, A. M. J.,, Khunti, K.,, Jansson, Stefan P. O.,, Mata-Cases, M.,, Seidu, S.,, Harris, S. B.,, Brunton, S.,, Topsever, P.,   +8 more
core   +1 more source

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

FEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil, Anna Corrà, Annalisa Scapolatiello, Chengxiang Qiu, Gianluca Amadei   +4 more
wiley   +1 more source

Intensification of the freeze drying process by the control of both freezing and primary drying steps

, 2013
The problem of optimization of freeze-drying cycles is addressed, with emphasis in both freezing and primary drying steps. In particular, this study shows that the control of the nucleation event produces more uniform batches (as ice nucleation is ...
Barresi, Antonello, Pisano, Roberto, Bullich, R., Oddone, Irene   +3 more
core  

Control of VSC-HVDC with electromechanical characteristics and unified primary strategy [PDF]

, 2016
High voltage dc (HVDC) systems act as the prevailed solution for transmitting offshore wind energy to onshore main grids. Control of the voltage source converters (VSC) in HVDC systems is decisive for the performance.
Rouzbehi, Kumars, Zhang, Weiyi, Rodríguez Cortés, Pedro, Candela García, José Ignacio, Luna Alloza, Álvaro   +4 more
core   +1 more source

2022 update to the position statement by Primary Care Diabetes Europe : a disease state approach to the pharmacological management of type 2 diabetes in primary care

, 2022
Type 2 diabetes and its associated comorbidities are growing more prevalent, and the complexity of optimising glycaemic control is increasing, especially on the frontlines of patient care. In many countries, most patients with type 2 diabetes are managed
Cos, X.,, Neijens, A. M. J.,, Khunti, K.,, Jansson, Stefan P. O.,, Mata-Cases, M.,, Seidu, S.,, Harris, S. B.,, Brunton, S.,, Topsever, P.,   +8 more
core   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source

The feasibility of assessing the Flinders Program™ of patient self-management in New Zealand primary care settings

, 2010
InTRODUCTIOn: The Flinders ProgramTM has been adopted in new Zealand as a useful and appropriate approach for self-management with primary care clients who have chronic conditions.
Bycroft, J, Horsburgh, Margaret, Roy, D, Miller, D, Goodyear-Smith, Felicity, Mahony, Faith, Donnell, E   +6 more
core  

Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes [PDF]

, 2014
SummaryObjectiveHedgehog signalling is mediated by the primary cilium and promotes cartilage degeneration in osteoarthritis. Primary cilia are influenced by pathological stimuli and cilia length and prevalence are increased in osteoarthritic cartilage ...
Knight, M.M., Chapple, JP, Chapple, J.P., Knight, MM, Thompson, CL, Thompson, C.L.   +5 more
core   +1 more source