Results 91 to 100 of about 12,079,078 (266)

Improving Mathematics Learning Outcomes through Contextual-Based Learning Video Media for Fourth Grade Elementary School Students

Jurnal Media dan Teknologi Pendidikan
This study was motivated by the low mathematics learning outcomes of elementary school students, which are attributed to the lack of connection between instructional materials and real-life contexts as well as the limited variation in teaching methods ...
Ni Made Aprelia Merti Dewi, Dewi Anzelina, Ikrima Maulida   +2 more
doaj   +1 more source

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

Molecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann, Eduardo García‐Galea, Alice O'Farrell, Zak Kinsella, Maxime Meylan, Florent Petitprez, Ingrid Arijs, Tom Venken, Hari Ps, Adrian Lärkeryd, Ian Miller, Janick Selves, Nadja Meindl‐Beinker, Fiorella Ruiz‐Pace, Elena Élez, Raquel Comas‐Navarro, Frank Lincoln, Dirk Fey, Gift Nyamundanda, Aoife Nolan, Joern Lewin, Raquel Perez‐Lopez, Jonathan Briody, Kathleen Bennett, Walter Kolch, David Matallanas, Alexander Kel, Enrique Arenas, Joaquín Arribas, Bart Ghesquière, Josep Tabernero, Julie Meilleroux, Deborah McNamara, Ray McDermott, Marvin Lim, Mary O'Reilly, Brian Bird, Lisa Stack, Lucia Moloney, Patrick Morris, Keith Egan, Maciej Milewski, Lars Scheuer, Joachim Behringer, Georg Bolz, Ramon Salazar, Cristina Santos, Andrea Ruiz, Orla Casey, Verena Murphy, Matthias Ebert, Livio Trusolino, Diether Lambrechts, Anguraj Sadanandam, Catherine Sautès‐Fridman, Jochen Prehn, Paolo Nuciforo, Jacques Fieschi, Florence Monville, Darran O'Connor, Wolf Fridman, Annette Byrne   +61 more
wiley   +1 more source

The Effect of the Catur Pramana Learning Cycle Method Using Augmented Reality Media on the Learning Outcomes of Grade 5 Primary School Students

Indonesian Journal of Instruction
The low student ability in understanding classroom learning materials indicates persistent problems in the learning process. This condition is influenced by the use of less varied instructional media, which tends to rely solely on videos from the ...
Ni Made Yuniari Kusuma Dewi, Ni Wayan Rati, Adrianus I Wayan Ilia Sukmana   +2 more
doaj   +3 more sources

Analysis of Fourth-Grade Students' Science Process Skills: A Comparative Descriptive Quantitative Study Between Sekolah Penggerak and Non-Sekolah Penggerak

Indonesian Journal of Instruction
The low mastery of science process skills among elementary school students poses a challenge in science education. This study aims to analyze the differences in science process skills among fourth-grade students in Sekolah Penggerak and Bukan Sekolah ...
Pande Putu Adhi Paramaarta, Putu Nanci Riastini, I Gede Astawan   +2 more
doaj   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Computational thinking in primary education: a systematic literature review

Research on Education and Media, 2019
This study presents a 13-year (2006–2018) systematic literature review related to the way that computational thinking (CT) has grown in elementary level education students (K-6) with the intention to: (a) present an overview of the educational context ...
P. Kakavas, F. Ugolini
semanticscholar   +1 more source

Capacity building for guidance and counseling teachers in coastal schools through narrative counseling to enhance students’ life meaning [PDF]

BIO Web of Conferences
This study aims to develop and evaluate a capacity-building framework for guidance and counseling teachers in coastal schools through the integration of narrative counseling approaches.
Wijaya Rasman Sastra, Suherman La Ode Achmad, Manan Manan, Tarno Tarno, Gawise Gawise, Jannah Nur, Rajab Gusrianda Bin   +6 more
doaj   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

Molecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute, Madeleine Birgersson, Paolo Ceriani, Margareta Wilhelm, Ourania N Kostopoulou   +4 more
wiley   +1 more source

Development of Teaching Materials Based on Differentiated Learning to Improve Critical Thinking Dimensions of The Pancasila Learner Profile

Jurnal Kependidikan
This research aims to develop teaching materials based on differentiated learning to improve critical thinking dimensions of the Pancasila Learner Profile for students in elementary schools.
Farhania Maulida, Andhin Dyas Fitriani, Mela Darmayanti   +2 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source