Results 31 to 40 of about 1,820,902 (262)
Jurnal KependidikanThis research aims at developing an Ethnoliteracy-based guided discovery learning model in writing imaginary stories at elementary schools. It used the research and development (R&D) method with 4D (Define, Design, Develop, and Disseminate) model ...
Riga Zahara Nurani +3 more
doaj +1 more source
Development of visuals card as educational media to improve student’s achievement on the science concept of “Human musculoskeletal system” for 5th grade of elementary school at Depok City [PDF]
Biotika, 2018 This research aimed to develop visual-based science learning media on human musculoskeletal system material as an effort to improve student’s achievement and understanding in mastering the material.
Dulyapit A., Sumantri S., Nurjannah
doaj
Facta Universitatis. Series, Teaching, Learning and Teacher Education, 2023 School as learning organization is a multi-level and multi-dimensional concept, incorporating characteristics of emotional climate such as trust, mutual support and respect, benefits to teachers and contributes to their job satisfaction.
Efstathios Xafakos +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source
Primary Physical Education [PDF]
European Physical Education Review, 2017 Physical Education is widespread across the world, yet despite its cultural variation it remains remarkably similar. The ability of the subject to replicate its practices makes it a potential site for exploration from a memetic perspective. The purpose of this paper is to examine documentary evidence such as research papers, policy documents and ...
Ward, Gavin, Griggs, Gerald
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
FEBS Letters, EarlyView.GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
Educational Case: Primary Osteosarcoma [PDF]
Academic Pathology, 2019 The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology.
Aldis H. Petriceks BA, Darren Salmi MD
openaire +3 more sources