Results 71 to 80 of about 5,406,250 (315)

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Bali Jejaitan Ethno-Education Digital Book with Integrated Material on Identifying Geometric Solids in Mathematics Learning

open access: yesJurnal Media dan Teknologi Pendidikan
Mathematics learning on spatial geometry material often feels abstract and less meaningful for elementary school students. The lack of contextual learning media and not linking the material to local culture is one of the causes of students' low ...
Ni Ketut Arini   +2 more
doaj   +1 more source

Capacity building for guidance and counseling teachers in coastal schools through narrative counseling to enhance students’ life meaning [PDF]

open access: yesBIO Web of Conferences
This study aims to develop and evaluate a capacity-building framework for guidance and counseling teachers in coastal schools through the integration of narrative counseling approaches.
Wijaya Rasman Sastra   +6 more
doaj   +1 more source

NATIONAL EDUCATION IN PRIMARY EDUCATION

open access: yes, 2022
In this article, the use of pedagogical technology, interactive methods and educational games in primary classes, modern information and communication technologies in the teaching of educational science in primary grades, teachers' use of independent thinking, creative research and logical thinking.
openaire   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

open access: yesMolecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed   +10 more
wiley   +1 more source

Balinese Local Wisdom-Based Animation Video to Improve Students’ Cultural Literacy

open access: yesJurnal Media dan Teknologi Pendidikan
The low cultural literacy of students is attributed to a lack of understanding of local wisdom in the area, and the learning media used are still not varied. This research aims to develop an animated video media based on Balinese local wisdom to enhance
I Kadek Nandiwardhana   +2 more
doaj   +1 more source

Primary education and secondary education [PDF]

open access: yesEducational Psychology, 2018
Like no other organised activity, primary and secondary education brings together people of different gender, social status, ability, and personality.
openaire   +1 more source

Aid and Universal Primary Education [PDF]

open access: yes
Universal Primary Education (UPE) is one of the main objectives of development aid. However, very little empirical evidence of its effectiveness actually exists.
Laurent Wagner, Rohen D'Aiglepierre
core  

How genomic information is accessed in clinical practice: an electronic survey of UK general practitioners. [PDF]

open access: yes, 2020
Genomic technologies are having an increasing impact across medicine, including primary care. To enable their wider adoption and realize their potential, education of primary health-care practitioners will be required.
Evans, WRH   +4 more
core   +2 more sources

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

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