Results 61 to 70 of about 1,503,702 (309)

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Innovation and adoption of energy efficient technologies: an exploratory analysis of Italian primary metal manufacturing SMEs

, 2013
Additional efforts will be needed by European countries to improve the energy efficiency, as with current trends the 20% objective will be missed. Small and medium-sized enterprises (SMEs) manufacturing sector is a promising field, as SMEs are less ...
Trianni, A., Cagno, E., Worrell E., Energy, Resources & Technological Change, CAGNO, ENRICO, Energy and Resources, TRIANNI, ANDREA, Worrell, E.   +7 more
core   +1 more source

POWER MANAGEMENT SAFETY IN EU AND THE ENERGY POLICY IN TRANSPORTATION

Contemporary Economy, 2015
EU countries face a serious problem of being too much dependent on the crude oil import. Transportation sector is especially dependent on import of fuels.
Ryszard Rolbiecki
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Energy balance related behaviour: personal, home- and friend-related factors among schoolchildren in Europe studied in the ENERGY-project [PDF]

, 2014
To design interventions that target energy balance-related behaviours, knowledge of primary schoolchildren's perceptions regarding soft drink intake, fruit juice intake, breakfast consumption, TV viewing and physical activity (PA) is essential.
Vik, Froydis N., Moreno, L., Saskia J te Velde, Luis Moreno, Singh, A., Singh, A.S., Natasa Jan, Singh, Amika S, Chinapaw, Mai, Bere, Elling, Moreno, Luis, Chinapaw, M., Chin A Paw, M.J.M., Elling Bere, Froydis N Vik, Vik, F.N., Mai Chinapaw, Bringolf-Isler, Bettina, Bringolf-Isler, B., Jan, N., te Velde, Saskia J, Vik, Frøydis N., Jan, Natasa, Yannis Manios, Vik, Froydis N, de Bourdeaudhuij, I., Kovacs, Eva, Amika Singh, Kovacs, E., Te Velde, S. J., Vik, F. N., Brug, Johannes, Johannes Brug, Bere, E., Froydis N. Vik, Brug, J., Manios, Yannis, Bettina Bringolf-Isler, Bringolf-Ilser, Bettina, Te Velde, Saskia J., Chinapaw, Mai JM, Singh, Amika, Ilse De Bourdeaudhuij, Eva Kovacs, De Bourdeaudhuij, Ilse, Bourdeaudhuij, Ilse de, te Velde, S.J., Manios, Y., Saskia J. te Velde   +48 more
core   +1 more source

From Primary to Final Energy Consumption - Analysing Structural and Efficiency Changes on the Energy Supply Side

, 2022
S.693-702A methodology for analyzing changes in Total Primary Energy Consumption (TPC) and the ratio of Total Primary to Total Final Energy Consumption (TFC) is presented using the principles of factor analysis.
Landwehr, M., Jochem, E.
core   +1 more source

Deep energy retrofits using different retrofit materials under different energy scenarios : life cycle cost and primary energy implications

, 2022
Building renovation is considered a key strategy to facilitating the transition towards a renewable energy system, mitigating climate change and addressing energy poverty.
Gustavsson, Leif, Piccardo, Chiara
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

Geothermal Heat Pumps and Their Impact on Building Energy Efficiency and Ecology

Energies
This article analyses the impact of ground-source heat pumps on the energy efficiency and environmental impact of a residential building, depending on the temperature of the ground source, the flow temperature of the heating system, and the domestic hot ...
Michał Kaczmarczyk
doaj   +1 more source