Results 71 to 80 of about 4,191,972 (346)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Low cost solar energy collection system [PDF]
, 1977 A fixed, linear, ground-based primary reflector having an extended, curved sawtooth contoured surface covered with a metallized polymeric reflecting material, reflected solar energy to a movably supported collector that was kept at the concentrated line ...
Miller, C. G., Stephans, J. B.
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Geothermal Heat Pumps and Their Impact on Building Energy Efficiency and Ecology
EnergiesThis article analyses the impact of ground-source heat pumps on the energy efficiency and environmental impact of a residential building, depending on the temperature of the ground source, the flow temperature of the heating system, and the domestic hot ...
Michał Kaczmarczyk
doaj +1 more source
Primary energy consumption in selected EU Countries compared to global trends
Open Chemistry, 2021 The article shows the consumption of primary energy carriers in selected European Union (EU) countries, including Poland. The trend of consumption of primary energy carriers was compared with the global trend, which is different from that observed in the
Olkuski Tadeusz +4 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Primary energy substitution models: On the interaction between energy and society [PDF]
Technological Forecasting and Social Change, 1977 This paper describes an attempt to develop a “synthetic” model of primary energy substitution, using certain rules which proved fruitful in describing the substitution of other commodities. This model will be used for forecasting, and for checking the validity of certain objectives set for R&D in the field of energy.
openaire +4 more sources
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
FEBS Letters, EarlyView.Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas +3 more
wiley +1 more source
An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane
FEBS Letters, EarlyView.Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa +3 more
wiley +1 more source