Results 41 to 50 of about 15,652,676 (359)

Foodborne Illness Outbreak Investigation Amongst Party Guests in Highfield Suburb, Harare City, Zimbabwe, 2020: A Retrospective Cohort Study

Journal of Interventional Epidemiology and Public Health
Background: On November 2, 2020, 5 patients presented at Highfield Polyclinic with fever, diarrhoea, abdominal pain, vomiting and some with dehydration after attending the same party on October 31, 2020.
Linda Nyasha Kanzara, Portia Manangazira, Emmanuel Govha, Tsitsi Patience Juru, Addmore Chadambuka, Notion Tafara Gombe, Maurice Omondi, Mufuta Tshimanga   +7 more
doaj   +1 more source

RAD50 missense variants differentially affect the DNA damage response and mitotic progression

FEBS Letters, EarlyView.
RAD50 incorporates into the MRN complex and initiates the DNA damage response. Furthermore, RAD50 promotes mitotic progression. RAD50 missense variants capable of forming an MRN complex supported the DNA damage response and mitotic features to different extents in complementation experiments, indicating these functions are separable and might impact ...
Hanna Redeker, Swantje Kebel, Lea Völkening, Anna Vatselia, Louisa Weinhold, Girmay Asgedom, Axel Schambach, Detlev Schindler, Thilo Dörk, Kristine Bousset   +9 more
wiley   +1 more source

COVID-19 booster vaccine acceptance in North Central Nigeria: An application of the Integrated Behavioural Model

Journal of Interventional Epidemiology and Public Health
Introduction: The limited protection durability of the primary COVID-19 vaccines and the existential threats of variants with evasive mechanisms have necessitated the need to roll out booster vaccines in many countries.
Abiodun Ebenezer Kolapo, Olubusayo Elizabeth Fakunle, Michael Sunday Oguntoye, Muhammad Shakir Balogun   +3 more
doaj   +1 more source

Primary singularities of vector fields on surfaces [PDF]

Geometriae Dedicata, 2019
Unless another thing is stated one works in the $C^\infty$ category and manifolds have empty boundary. Let $X$ and $Y$ be vector fields on a manifold $M$. We say that $Y$ tracks $X$ if $[Y,X]=fX$ for some continuous function $f\colon M\rightarrow\mathbb R$.
Hirsch, MW, Turiel, FJ
openaire   +4 more sources

Plasmodium falciparum gametogenesis essential protein 1 (GEP1) is a transmission‐blocking target

FEBS Letters, EarlyView.
This study shows Plasmodium falciparum GEP1 is vital for activating sexual stages of malarial parasites even independently of a mosquito factor. Knockout parasites completely fail gamete formation even when a phosphodiesterase inhibitor is added. Two single‐nucleotide polymorphisms (V241L and S263P) are found in 12%–20% of field samples.
Frederik Huppertz, Milagros Siebeck Caturelli, Lina S. Lehmann, Florian Kurth, Alexander G. Maier, Kai Matuschewski   +5 more
wiley   +1 more source

Neural Field Model of Receptive Field Restructuring in Primary Visual Cortex

Neural Computation, 2001
Receptive fields (RF) in the visual cortex can change their size depending on the state of the individual. This reflects a changing visual resolution according to different demands on information processing during drowsiness. So far, however, the possible mechanisms that underlie these size changes have not been tested rigorously.
Suder, Katrin, Wennekers, Thomas, Wörgötter, Florentin   +2 more
openaire   +3 more sources

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Characteristics and outcomes of COVID-19 patients hospitalized at a Central Hospital in Harare, 2020-2022

Journal of Interventional Epidemiology and Public Health
Introduction: In June 2021, Zimbabwe experienced a third COVID-19 wave characterized by a 3.5% case fatality rate compared to 1.5% in the first wave and 2.6% in the second wave. Sixty-eight percent of these deaths were among hospitalized patients.
Linda Nyasha Kanzara, Isaac Phiri, Hamufare Dumisani Mugauri, Addmore Chadambuka, Tsitsi Patience Juru, Gerald Shambira, Notion Tafara Gombe, Mufuta Tshimanga   +7 more
doaj   +1 more source

Descriptive Epidemiology and Mortality Risk Factors of COVID-19 Outbreak in Delta State, Nigeria, March – August 2020

Journal of Interventional Epidemiology and Public Health, 2021
Introduction: The highly contagious Coronavirus Disease 2019 (COVID-19) was first confirmed in Nigeria on February 27, 2020. In Delta State, the first COVID-19 case was recorded on April 7, 2020, which spread across the state.
Adaora Rosemary Ejikeme, Bola Biliaminu Lawal, Shalom Ogbonna, Ehimario Igumbor, Mildred Okowa, Ivie Airefetalor, Daniel Otoh, Angela Okocha-Ejeko, Onyinyechi Emefiene, Ann Ojimba, Henry Uguru-Ekechi, Rhoda Atteh, Nkiruka Obiazor, Chukwuma David Umeokonkwo, Muhammad Shakir Balogun, Oladipupo Ipadeola, Abdulhakeem Abayomi Olorukooba, Aboyowa Edukugho, Bolaji Ahmed, Oladipo Ogunbode   +19 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source