Results 61 to 70 of about 2,243,380 (315)

Tuberculosis Notification Surveillance System Evaluation in Bulilima District Zimbabwe, 2020

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: The World Health Organisation (WHO) recommends the detection of 90% of WHO's estimated TB incidence. In 2020 Bulilima District detected 31% of Zimbabwe`s estimated incidence thereby failing to meet the WHO detection target.
Mutizwa Thomas Mupedziswa   +7 more
doaj   +1 more source

Chiral primary one-point functions in the D3-D7 defect conformal field theory [PDF]

open access: yes, 2013
JHEP is an open-access journal funded by SCOAP3 and licensed under CC BY 4.0archiveprefix: arXiv primaryclass: hep-th reportnumber: NORDITA-2012-81 slaccitation: %%CITATION = ARXIV:1210.7015;%%archiveprefix: arXiv primaryclass: hep-th reportnumber ...
Semenoff, Gordon W.   +8 more
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Evaluation of Surveillance System for Adverse Drug Reaction Due to Antiretroviral Drugs, Mazowe District, Zimbabwe, 2021

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Antiretroviral drugs (ARVs) are associated with the occurrence of adverse drug reactions (ADRs). The Medicines Control Authority of Zimbabwe requires that all ADRs be reported within 15 days of detection.
Godwin Choga   +7 more
doaj   +1 more source

Recurrences and second primary breast cancers in older women with initial early-stage disease.

open access: yes, 2009
BACKGROUND: The association between common breast cancer therapies and recurrences and second primary breast cancers in older women is unclear, although older women are less likely to receive common therapies.
Enger, Shelley M.   +10 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Knowledge, risk perception and uptake of COVID-19 vaccination among internally displaced persons in complex humanitarian emergency setting, Northeast Nigeria

open access: yesBMC Public Health
Background Owing to crowded and unsanitary conditions, internally displaced persons (IDPs) have an increased risk of COVID-19 infection. Adoption of COVID-19 preventive measures among this population is premised on accurate information, adequate ...
Saheed Gidado   +21 more
doaj   +1 more source

Improving timeliness of routine primary healthcare data: Healthcare workers’ perspectives on a prompt-enabled responsive feedback mechanism in Northern Nigeria, 2022

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Poor data quality from health facilities in Nigeria remains a significant barrier to effective decision-making. One identified contributor is the delay in documenting data at the point of service.
Clara Oguji   +14 more
doaj   +1 more source

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

open access: yesMolecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov   +3 more
wiley   +1 more source

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