Results 71 to 80 of about 2,243,380 (315)

Taking ownership of your maths curriculum: the role of research in moving us away from 'Stepford' teaching [PDF]

open access: yes
Taking ownership of your primary mathematics curriculum - the role of research in moving us away from 'Stepford' teaching Caught up in an overly prescriptive curriculum, our talented teachers can sometimes lose sight of what they are doing, and why ...
Field, Jenny
core  

Cell type specific connections from primary motor to primary somatosensory cortex. [PDF]

open access: yes, 2013
Anatomical studies have shown that primary somatosensory (S1) and primary motor (M1) cortices are reciprocally connected. The pathway from primary motor cortex (M1) to primary somatosensory cortex (S1) is thought to influence activity in S1 by ...
Kinnischtzke, Amanda K
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Management of chlamydia and gonorrhoea infections diagnosed in primary care using a centralised nurse-led telephone-based service: mixed methods evaluation

open access: yesBMC Family Practice, 2020
Background Up to 18% of genital Chlamydia infections and 9% of Gonorrhoea infections in England are diagnosed in Primary Care. Evidence suggests that a substantial proportion of these cases are not managed appropriately in line with national guidelines ...
Jeremy Horwood   +6 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Prevalence and Risk Factors of Elevated Blood Lead in Children in Gold Ore Processing Communities, Zamfara, Nigeria, 2012

open access: yesJournal of Health and Pollution, 2016
Background. In March 2010, Medecins Sans Frontieres/Doctors Without Borders detected an outbreak of acute lead poisoning in Zamfara State, northwestern Nigeria, linked to low-technology gold ore processing.
John A. Kaufman   +10 more
doaj   +1 more source

Epidemiological profile of the Ebola virus disease outbreak in Nigeria, July-September 2014

open access: yesThe Pan African Medical Journal, 2015
INTRODUCTION: in July 2014, Nigeria experienced an outbreak of Ebola virus disease following the introduction of the disease by an ill Liberian Traveler.
Emmanuel Onunche Musa   +17 more
doaj   +1 more source

Universal Generators for Primary Closures of Galois Fields [PDF]

open access: yes, 2001
If \( \bar{F} \) is an algebraic closure of a Galois field F, then for each integer n ≥ 1 there is exactly one subfield E n of \( \bar{F} \) containing F and having degree n over F. For a prime number r, we consider the r-primary closure \( {\bar{F}_{r}}: = \bigcup {_{{m \geqslant 0}}{E_{{{r^{m}}}}}} \) over F and prove, under the assumption that r ≥ 7,
openaire   +1 more source

The impact of sound field systems on learning and attention in elementary school classrooms [PDF]

open access: yes, 2012
Purpose: An evaluation of the installation and use of sound field systems (SFS) was carried out to investigate their impact on teaching and learning in elementary school classrooms.
Shield, Bridget   +9 more
core   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Home - About - Disclaimer - Privacy