Epidemiological profile of the Ebola virus disease outbreak in Nigeria, July-September 2014
INTRODUCTION: in July 2014, Nigeria experienced an outbreak of Ebola virus disease following the introduction of the disease by an ill Liberian Traveler.
Emmanuel Onunche Musa +17 more
doaj +1 more source
Unlocking the potential of cell‐permeable nanobodies for intracellular applications
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés +2 more
wiley +1 more source
Background Up to 18% of genital Chlamydia infections and 9% of Gonorrhoea infections in England are diagnosed in Primary Care. Evidence suggests that a substantial proportion of these cases are not managed appropriately in line with national guidelines ...
Jeremy Horwood +6 more
doaj +1 more source
Universal Generators for Primary Closures of Galois Fields [PDF]
If \( \bar{F} \) is an algebraic closure of a Galois field F, then for each integer n ≥ 1 there is exactly one subfield E n of \( \bar{F} \) containing F and having degree n over F. For a prime number r, we consider the r-primary closure \( {\bar{F}_{r}}: = \bigcup {_{{m \geqslant 0}}{E_{{{r^{m}}}}}} \) over F and prove, under the assumption that r ≥ 7,
openaire +1 more source
Evidence informed practice in Primary Education: an unintended but valuable resource
This considers the potential of the Teacher Training Resource Bank (TTRB) as a resource for professional development with primary education. Although, the portal was designed with the needs of Teacher Education in mind, the resource has been evaluated as
Blamires, M. +1 more
core
Field Cancerisation of the Upper Aerodigestive Tract: Screening for Second Primary Cancers of the Oesophagus in Cancer Survivors [PDF]
Tobacco, alcohol, and betel quid are the main causes of squamous cell cancers of the upper aerodigestive tract. These substances can cause multifocal carcinogenesis leading to multiple synchronous or metachronous cancers of the oesophagus, head and neck
Güllü Cataldegirmen +5 more
core
Comparing the paths of Hedgehog release in artificial and natural settings
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley +1 more source
How structural disorder and polyelectrolyte properties of prothymosin α enable its large interactome
In this review, complexes of the fully disordered and highly negatively charged prothymosin α are collected, described, and discussed. Linked to its poly‐electrostatic character, prothymosin α engages a large interactome through multiple different binding modes ranging from fully disordered complexes to short linear motif (SLiM)‐driven interactions ...
Ketty C. Tamburrini +3 more
wiley +1 more source
Triploid Atlantic salmon (Salmo salar) may have increased risk of primary field outbreaks of infectious salmon anaemia. [PDF]
Aunsmo A +7 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source

