Results 41 to 50 of about 33,684 (218)
Generators for primary closures of Galois fields
Let \(q\) be a prime power, \(k\) and \(e\) positive integers and \((\mathbb F_q,\mathbb F_{q^k},\mathbb F_{q^{ek}})\) a tower of finite fields of order \(q\), \(q^k\) and \(q^{ek}\), respectively. Let \({\mathcal F}\) denote the set of triples \((q,k,e)\) for which, for every \(a\in \mathbb F_{q^k}\) normal over \(\mathbb F_q\) (i.e.\ \(\{a,a^q,\dots ...
openaire +1 more source
Neural Field Model of Receptive Field Restructuring in Primary Visual Cortex
Receptive fields (RF) in the visual cortex can change their size depending on the state of the individual. This reflects a changing visual resolution according to different demands on information processing during drowsiness. So far, however, the possible mechanisms that underlie these size changes have not been tested rigorously.
Suder, Katrin +2 more
openaire +3 more sources
Primary singularities of vector fields on surfaces [PDF]
Unless another thing is stated one works in the $C^\infty$ category and manifolds have empty boundary. Let $X$ and $Y$ be vector fields on a manifold $M$. We say that $Y$ tracks $X$ if $[Y,X]=fX$ for some continuous function $f\colon M\rightarrow\mathbb R$.
Hirsch, MW, Turiel, FJ
openaire +4 more sources
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace +6 more
wiley +1 more source
Phosphoinositides and inositol phosphates as molecular glues
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry +9 more
wiley +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Tuberculosis Notification Surveillance System Evaluation in Bulilima District Zimbabwe, 2020
Introduction: The World Health Organisation (WHO) recommends the detection of 90% of WHO's estimated TB incidence. In 2020 Bulilima District detected 31% of Zimbabwe`s estimated incidence thereby failing to meet the WHO detection target.
Mutizwa Thomas Mupedziswa +7 more
doaj +1 more source

