Results 181 to 190 of about 4,620,636 (276)

Selected Factors of Vascular Changes: The Potential Pathological Processes Underlying Primary Headaches in Children. [PDF]

open access: yesChildren (Basel), 2022
Sordyl J   +5 more
europepmc   +1 more source

The Japanese Adaptation of the Reading the Mind in Films Test: Differentiating Autism Spectrum Disorder From Depression Using an Ecologically Valid Social Cognitive Task

open access: yesAutism Research, EarlyView.
ABSTRACT Cognitive tests that reflect the complexity of real‐world social interactions are essential for autism spectrum disorder (ASD)‐related clinical assessment and research. This study developed and adapted a Japanese version of the Reading the Mind in Films (RMF) test, which assesses mind‐reading ability through dynamic, multisensory, and context ...
Sayaka Kawakami   +3 more
wiley   +1 more source

Efficacy, safety and cost‐effectiveness of CAR‐T therapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
CAR T‐cells demonstrate high efficacy in blood cancers, including ALL, MM and DLBCL. Innovations target solid tumours despite challenges such as antigen escape. Combination therapies enhance the delivery and infiltration of CAR T cells. Toxicity, cost and resistance remain major barriers to clinical use.
Emina Karahmet Sher   +7 more
wiley   +1 more source

[Development and validation of Cefalytics: an artificial intelligence-based application for the rapid diagnosis of primary headaches]. [PDF]

open access: yesAten Primaria
Martínez Simón J   +5 more
europepmc   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad   +4 more
wiley   +1 more source

Repeated intradermal lipopolysaccharide challenge responses in healthy volunteers: Implications for clinical pharmacology studies

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Intradermal application of lipopolysaccharide (LPS), a Toll‐like receptor 4 agonist, induces a local inflammatory response and is used as a human challenge model to evaluate the pharmacodynamics of investigational medicinal products. While currently applied in a single, parallel‐group setting, alternative within‐subject designs involving repeated ...
Alexandra A. J. Sillé   +12 more
wiley   +1 more source

Associations between sleep bruxism and primary headaches: a descriptive study. [PDF]

open access: yesJ Oral Facial Pain Headache
Réus JC   +6 more
europepmc   +1 more source

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