Results 111 to 120 of about 4,356,366 (357)

Work satisfaction and future career intentions of experienced nurses transitioning to primary health care employment

Journal of Nursing Management, 2018
AIM To explore registered nurses' reflections on transitioning from acute to primary health care employment, and future career intentions. BACKGROUND Reforms in primary health care have resulted in increasing demands for a skilled primary health care ...
C. Ashley, K. Peters, Angela Brown, E. Halcomb   +3 more
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Change in physical activity level and clinical outcomes in older adults with knee pain: a secondary analysis from a randomised controlled trial

BMC Musculoskeletal Disorders, 2018
Background Exercise interventions improve clinical outcomes of pain and function in adults with knee pain due to osteoarthritis and higher levels of physical activity are associated with lower severity of pain and higher levels of physical functioning in
Jonathan G. Quicke, Nadine E. Foster, Peter R. Croft, Reuben O. Ogollah, Melanie A. Holden   +4 more
doaj   +1 more source

Primary Health Care as a Foundation for Strengthening Health Systems in Low- and Middle-Income Countries

Journal of general internal medicine, 2016
Primary health care (PHC) has been recognized as a core component of effective health systems since the early part of the twentieth century. However, despite notable progress, there remains a large gap between what individuals and communities need, and ...
A. Bitton, Hannah L Ratcliffe, J. Veillard, D. Kress, Shannon Barkley, M. Kimball, F. Secci, Ethan Wong, Lopa Basu, C. Taylor, J. Bayona, Hong Wang, Gina Lagomarsino, L. Hirschhorn   +13 more
semanticscholar   +1 more source

Exploration of heterogeneity and recurrence signatures in hepatocellular carcinoma

Molecular Oncology, EarlyView.
This study leveraged public datasets and integrative bioinformatic analysis to dissect malignant cell heterogeneity between relapsed and primary HCC, focusing on intercellular communication, differentiation status, metabolic activity, and transcriptomic profiles.
Wen‐Jing Wu, Jianchao Wang, Fuqing Chen, Xuefeng Wang, Bin Lan, Ruyi Fu, Hong Wen, Fangfang Chen, Wei Hong, Tian‐Yu Tang, Ying He, Gang Chen, Jianyin Zhou, Hai‐Long Piao, Di Chen, Shu‐Yong Lin   +15 more
wiley   +1 more source

Subgrouping patients with sciatica in primary care for matched care pathways: development of a subgrouping algorithm

BMC Musculoskeletal Disorders, 2019
Background Sciatica is a painful condition managed by a stepped care approach for most patients. Currently, there are no decision-making tools to guide matching care pathways for patients with sciatica without evidence of serious pathology, early in ...
Kika Konstantinou, Kate M. Dunn, Danielle van der Windt, Reuben Ogollah, Vinay Jasani, Nadine E. Foster, the SCOPiC study team   +6 more
doaj   +1 more source

Nursing competency standards in primary health care: an integrative review.

Journal of Clinical Nursing, 2016
AIMS AND OBJECTIVES This paper reports an integrative review of the literature on nursing competency standards for nurses working in primary health care and, in particular, general practice.
E. Halcomb, M. Stephens, J. Bryce, Elizabeth Foley, C. Ashley   +4 more
semanticscholar   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Identifying key items to be addressed by non-clinical operators to manage out-of-hours telephone triage services for older adults seeking non-urgent unplanned care in Belgium: an e-Delphi study

BMC Health Services Research
Background This study aimed to achieve expert consensus regarding key items to be addressed by non-clinical operators using computer-software integrated medical dispatch protocols to manage out-of-hours telephone triage (OOH-TT) services for calls ...
Farah Islam, Pieter Heeren, Kelu Yang, Koen Milisen, Marc Sabbe   +4 more
doaj   +1 more source

A qualitative study on African immigrant and refugee families’ experiences of accessing primary health care services in Manitoba, Canada: it’s not easy!

International Journal for Equity in Health, 2017
BackgroundImmigrant and refugee families form a growing proportion of the Canadian population and experience barriers in accessing primary health care services.
R. Woodgate, D. Busolo, Mary M. Crockett, R. Dean, Miriam R. Amaladas, P. Plourde   +5 more
semanticscholar   +1 more source