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Clinical features and mutational analysis of X-linked agammaglobulinemia patients in Malaysia
BackgroundBruton’s tyrosine kinase (BTK) is a cytoplasmic protein involved in the B cell development. X-linked agammaglobulinemia (XLA) is caused by mutation in the BTK gene, which results in very low or absent B cells.
Chai Teng Chear+17 more
doaj +1 more source
Local Immunodeficiency: Role of Neutral Viruses [PDF]
This paper analyzes the role of neutral viruses in the phenomenon of local immunodeficiency. We show that, even in the absence of altruistic viruses, neutral viruses can support the existence of persistent viruses, and thus local immunodeficiency. However, in all such cases neutral viruses can maintain only bounded (relatively small) concentration of ...
arxiv
The emergence and evolution of the research fronts in HIV/AIDS research [PDF]
In this paper, we have identified and analyzed the emergence, structure and dynamics of the paradigmatic research fronts that established the fundamentals of the biomedical knowledge on HIV/AIDS. A search of papers with the identifiers "HIV/AIDS", "Human Immunodeficiency Virus", "HIV-1" and "Acquired Immunodeficiency Syndrome" in the Web of Science ...
arxiv +1 more source
We report the updated classification of primary immunodeficiencies compiled by the Primary Immunodeficiency Expert Committee (PID EC) of the International Union of Immunological Societies (IUIS).
C. Picard+17 more
semanticscholar +1 more source
Treatment of primary immunodeficiency with allogeneic transplant and gene therapy.
The treatment of primary immunodeficiency disorders with allogeneic hematopoietic cell transplantation (HCT) has a history dating back to 1968 with the first successful transplant for a patient with severe combined immunodeficiency (SCID).
S. Pai
semanticscholar +1 more source
Background: Intestinal parasitic infection in immunodeficient patients especially those with impaired cellular immunity, like neoplasia, renal or heart transplant needs careful consideration.
A. Esteghamati+4 more
semanticscholar +1 more source
Arthritis and X-linked agammaglobulinemia [PDF]
Primary immunodeficiencies are defined as genetically determined functional and/or quantitative abnormalities in one or more of the components of the immune system.
Chieira, C+5 more
core
Conditioning Regimens for Hematopoietic Cell Transplantation in Primary Immunodeficiency
Hematopoietic cell transplantation (HCT) is an established curative treatment for children with primary immunodeficiencies. This article reviews the latest developments in conditioning regimens for primary immunodeficiency (PID).
S. Lum+5 more
semanticscholar +1 more source
Understanding the process of envelope glycoprotein incorporation into virions in simian and feline immunodeficiency viruses [PDF]
The lentiviral envelope glycoproteins (Env) mediate virus entry by interacting with specific receptors present at the cell surface, thereby determining viral tropism and pathogenesis.
Affranchino, Jose Luis+1 more
core +4 more sources