Results 51 to 60 of about 7,023,991 (280)

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

Ability of modal analysis to detect osseointegration of implants in transfemoral amputees : a physical model study [PDF]

, 2013
Owing to the successful use of non-invasive vibration analysis to monitor the progression of dental implant healing and stabilization, it is now being considered as a method to monitor femoral implants in transfemoral amputees.
Cairns, Nicola, Pearcy, Mark, Adam, Clayton, Smeathers, James   +3 more
core   +4 more sources

Comparative evaluation of implant stability in two different implant systems at baseline and 3–4 months intervals using RFA device (OSSTELL ISQ)

Indian Journal of Dental Research, 2019
Introduction: Osseointegration as formulated by Alberktson is crucial for implant survival and success. Osseointegration is a measure of implant stability.
Vidya Hiranmayi Kastala, Mulpuri Venkata Ramoji Rao   +1 more
doaj   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Enhancement of Primary Stability of Dental Implants Using Cortical Satellite Implants

Implant Dentistry, 2002
This study aims to assess the effect of satellite implants on the primary stability of dental implants placed in fresh extraction sites in vitro.34 titanium screw implants (3.75 mm x 10 mm; Bego, Bremen, Germany) were inserted in premolar- and molar-fresh extraction sites in domestic pig mandibles.
Engelke, Wilfried, Stahr, Stefanie, Schwarzwäller, Wolfgang   +2 more
openaire   +3 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Osseodensification implant site preparation technique and subsequent implant stability: A pilot study

Journal of Orthodontic Science, 2022
OBJECTIVE: The objective of the present study was to evaluate and compare primary and secondary implant stability of conical endosteal implants placed using osseodensification osteotomy and conventional osteotomy techniques.
Kurian Punnoose, G Arun Kumar, B Mahesh, Rajtilak Govindarajulu, V Amalorpavam, A Ebinu, J Suresh Babu, C Swarnalatha, Abhishek Singh Nayyar   +8 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

FEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas, Shahoon Khan, Abhishek Sharma, Byoungchun Lee, Savraj S. Grewal   +4 more
wiley   +1 more source

Influence of titanium and titanium-zirconium alloy as implant materials on implant stability of maxillary implant retained overdenture: a randomized clinical trial

BMC Oral Health
Background Long-term success of implant restoration depends on many factors one of them is the sufficient implant stability which is lowered in compromised bone density sites such as the maxilla as it is categorized as type III & IV bone, so searching ...
Amany Ibrahim Abd El-Hady, Hany Ibrahim Eid, Shaimaa Lotfy Mohamed, Sawsan Maged Fadl   +3 more
doaj   +1 more source