Results 71 to 80 of about 7,023,991 (280)

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

THE EFFECT OF OSSEODENSIFICATION TECHNIQUE ON IMPLANT PLACEMENT IN THE MAXILLARY POSTERIOR REGION (CLINICAL AND RADIOGRAPHICAL STUDY) [PDF]

Alexandria Dental Journal
Background: Dental implant became one of the most effective treatment modalities for replacing edentulous area. Since, bone density is an important factor affecting implant success, therefore, low bone density decreases chance for obtaining accepted ...
Fadel Sallat, Ahmed El Mahallawy, Aya Sakr   +2 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Validation of Resonance Frequency Analysis by Comparing Implant Stability Quotient Values With Histomorphometric Data

, 2011
The study was designed to determine the relationship between implant stability quotient (ISQ) values measured using resonance frequency analysis (RFA) and implant-bone distance measured histomorphometrically.
K. Chandrasekharan Nair, E. Munirathnam Naidu, Gomathinayagam Sivagami, Ashish Thomas Kunnekel   +3 more
core   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

FEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda, Sreerama Chaitanya Sridhara, Aura Carreira   +2 more
wiley   +1 more source

Primary stability and osseointegration comparing a novel tapered design tissue-level implant with a parallel design tissue-level implant. An experimental in vivo study. [PDF]

OBJECTIVES: The aim of the present study was to compare a novel tapered, double-threaded self-tapping tissue-Level design implant (TLC) to a well-established parallel walled tissue-level (TL) implant in terms of primary and secondary stability over time.
Rawlinson, S, Rawlinson, Simon, Pippenger, B, Shahdad, Shakeel, Gill, T, Shahdad, S, Pippenger, Benjamin, Kühl, Sebastian, Gill, Thomas, Kühl, S, Bellon, B, Bellon, Benjamin   +11 more
core   +2 more sources

Effects of implant thread design on primary stability—a comparison between single- and double-threaded implants in an artificial bone model

International Journal of Implant Dentistry, 2020
Background Primary implant stability is essential for osseointegration. To increase stability without changing the implant size, the thread length must be extended by reducing pitch, using a double-threaded implant, or reducing pitch/lead and lead angle ...
Yoko Yamaguchi, Makoto Shiota, Masaki Fujii, Masahiro Shimogishi, Motohiro Munakata   +4 more
doaj   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Measurement of primary stability of the dental implant and the influence of the implant design [PDF]

, 2017
1 SUMMARY Measurement of primary stability of the dental implant and the influence of the implant de- sign Primary stability is the lack of mobility in the bone after an implant insertion and it is conditioned by the quality and quantity of the bone, the
Dzan, Ladislav
core  

Comparison of Implant Stability Using Resonance Frequency Analysis: Osteotome versus Conventional Drilling

Frontiers in Dentistry, 2016
Objectives: Implant primary stability is one of the important factors in achieving implant success. The osteotome technique may improve primary stability in patients with poor bone quality. The aim of this study was to compare implant stability using two
Rokhsareh Sadeghi, Amir Reza Rokn, Asghar Miremadi   +2 more
doaj