Results 71 to 80 of about 890,728 (306)

Population screening for colorectal cancer means getting FIT:the past, present, and future of colorectal cancer screening using the fecal immunochemical test for hemoglobin (FIT) [PDF]

, 2014
Fecal immunochemical tests for hemoglobin (FIT) are changing the manner in which colorectal cancer (CRC) is screened. Although these tests are being performed worldwide, why is this test different from its predecessors?
Halloran, SP, Fraser, Callum G., Fraser, CG, Young, Graeme P., Halloran, Stephen P., Allison, JE, Allison, James E., Young, GP   +7 more
core   +1 more source

Comprehensive multi-phase 3D contrast-enhanced CT imaging for primary liver cancer

Scientific Data
Primary liver cancer is a significant global health issue with high incidence and mortality rates worldwide. Accurate diagnosis and classification of its subtypes are crucial for choosing the right treatment options and improving patient outcomes ...
Jiawei Luo, Xiaoyu Wan, Jinchao Du, Li Liu, Ling Zhao, Xin Peng, Min Wu, Shixin Huang, Xixi Nie   +8 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The burden of primary liver cancer and underlying etiologies from 1990 to 2015 at the global, regional, and national level: Results from the Global Burden of Disease Study 2015

, 2017
Importance Liver cancer is among the leading causes of cancer deaths globally. The most common causes for liver cancer include hepatitis B virus (HBV) and hepatitis C virus (HCV) infection and alcohol use.
Hay, Simon, Collaboration,, Global Burden of Disease Liver Cancer   +1 more
core   +1 more source

Primary liver cancer organoids and their application to research and therapy

Journal of the National Cancer Center
Primary liver cancer is a leading cause of death worldwide. To create advanced treatments for primary liver cancer, studies have utilized models such as 2D cell culture and in vivo animal models.
Xiaobin Zhu, Rajiv Trehan, Changqing Xie
doaj   +1 more source

Sex disparities in alcohol-associated liver disease and subtype differences in alcohol-attributable cancers in the United States [PDF]

Clinical and Molecular Hepatology
Background/Aims Harmful alcohol use is a substantial contributor to liver diseases, liver cancer, and extrahepatic neoplasms. Patterns of alcohol consumption have shifted over recent decades.
Pojsakorn Danpanichkul, Yanfang Pang, Tanuj Mahendru, Primrose Tothanarungroj, Luis Antonio Díaz, Juan Pablo Arab, Pimtawan Jatupornpakdee, Mark D. Muthiah, Kwanjit Duangsonk, Won-Mook Choi, Daniel Q. Huang, Donghee Kim, Mazen Noureddin, Karn Wijarnpreecha, Suthat Liangpunsakul, Amit G. Singal, Ju Dong Yang   +16 more
doaj   +1 more source

Expression and Clinical Significance of lnc RNA HOXA11-AS in Hepatocellular Carcinoma

Zhongliu Fangzhi Yanjiu, 2020
Objective To investigate the expression and clinical significance of long-chain non-coding RNA(lncRNA) HOXA11-AS in hepatocellular carcinoma. Methods We included 106 patients with primary liver cancer.
LI Bo, LYU Ming, ZHOU Shuai
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Consensus Development from the 5th Asia-Pacific Primary Liver Cancer Expert Meeting (APPLE 2014)

, 2015
A key mission of the Asia-Pacific Primary Liver Cancer Expert (APPLE) Association is to ensure a coherent view for management of hepatocellular carcinoma (HCC) and to advance new treatment for this difficult disease.
한광협, 성진실
core   +2 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source