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A study on the association between serum antiphospholipase A2 receptor antibodies and the hypercoagulable state in Chinese patients with primary membranous nephropathy. [PDF]
Ren FailLiu B, Qin Q, He S.
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Treatment options for patients with high anti-PLA2R antibodies in primary membranous nephropathy: a single-center cohort retrospective study. [PDF]
BMC NephrolCao H, Li X, Ke B.
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Cytokines Network in Primary Membranous Nephropathy
International Immunopharmacology, 2022There have been extensive studies on the immunological mechanism of primary membranous nephropathy (PMN). Autoantibodies, being the end product of humoral auto-immunity, matter much in diagnosis, therapy and prediction. Although PMN has been thought of as oligoinflammatory glomerulopathy, autoimmune diseases usually involve inflammation and it may be ...
Zhendong Feng, Yuehong Hu, Haoran Dai
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Pharmacological Treatment of Primary Membranous Nephropathy in 2016 [PDF]
Expert Review of Clinical Pharmacology, 2016 Therapy in patients with primary membranous nephropathy is debated. The discovery of anti-PLA2R antibodies provides opportunities for new treatment strategies. Areas covered: The PubMed database and Cochrane library were searched for full-text articles published in English before March 2016.
Jack F M Wetzels +2 more
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Primary membranous nephropathy: an endless story
Journal of Nephrology, 2022Abstract Primary membranous nephropathy (PMN) is an autoimmune disease caused by the attack of autoantibodies against podocyte antigens leading to the in situ production of immune complexes. However, the etiology is unknown and the pathogenesis is still far from being completely elucidated. MN is prevalently idiopathic or primary, but
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Translational Aspects of Primary Membranous Nephropathy
Seminars in Nephrology, 2017Membranous nephropathy (MN) in an autoimmune disease caused by binding of circulating antibodies to podocytic antigens. The search for the responsible target antigens has extended for more than 50 years and led to the identification of the major pathomechanisms leading to MN.
Elion, Hoxha, Rolf A K, Stahl
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Rituximab for the Treatment of Primary Membranous Nephropathy
Canadian Journal of Health Technologies, 2022Membranous nephropathy is an autoimmune disease and one of the most common causes of nephrotic syndrome in adults. The incidence of membranous nephropathy is 1.2 in 100,000 persons per year worldwide. Approximately 80% of patients with membranous nephropathy have a classification of primary (or idiopathic) membranous nephropathy.
Saadul Islam +12 more
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Primary membranous nephropathy in adolescence: A prospective study
Nephrology, 2017AbstractAimPrimary membranous nephropathy (PMN) accounts for only 1–2% of nephrotic syndrome in children. Antibodies to m‐type phospholipase A2 receptor (aPLA2R) is seen in 70% of adult PMN cases. The present study was undertaken to study m‐type phospholipase A2 receptor (PLA2R) status and clinical behavior in adolescent PMN cases.MethodsThe present ...
Vinod, Kumar +11 more
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Primary membranous nephropathy: comprehensive review and historical perspective
Postgraduate Medical Journal, 2019AbstractMembranous nephropathy (MN) is the most common cause of nephrotic syndrome in non-diabetic Caucasian adults over 40 years of age. It has an estimated incidence of 8–10 cases per 1 million. Fifty per cent of patients diagnosed with primary MN continue to have nephrotic syndrome and 30% of patients may progress to end-stage renal disease over 10 ...
Krishna C Keri +4 more
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