Results 11 to 20 of about 26,210 (158)
PRIMARY OPEN-ANGLE GLAUCOMA [PDF]
Primary open-angle glaucoma (POAG), by far the most common form of glaucoma, currently afflicts more than 2 million Americans, more than half of whom probably don't know they have it. Asymptomatic in the early stages, it gradually and progressively reduces the visual field and leads to blindness if untreated.
Nancy C, Sharts-Hopko +1 more
+8 more sources
Etiopathogenesis of primary open-angle glaucoma [PDF]
The article reviews literature covering the etiopathogenesis and risk factors for the development of primary open-angle glaucoma (POAG). Currently, this problem is one of the most complex and controversial in ophthalmology. The review considers the main theories: vascular, mechanical (retentional, hydromechanical), dystrophic (theory of primary ...
N V, Eliseeva, M I, Churnosov
openaire +2 more sources
The genetics of primary open angle glaucoma [PDF]
The advent of the discipline of molecular genetics over the past decade has led to a dramatic growth in our understanding of the genetics of a myriad of diseases. Ophthalmology has benefited greatly from this new technology, with significant advances in our knowledge about conditions as varied as aniridia and retinitis pigmentosa.1 2 Our understanding ...
A, Booth +4 more
openaire +2 more sources
Neuroinflammation in Primary Open-Angle Glaucoma [PDF]
Primary open-angle glaucoma (POAG) is the second leading cause of irreversible blindness worldwide. Increasing evidence suggests oxidative damage and immune response defects are key factors contributing to glaucoma onset. Indeed, both the failure of the trabecular meshwork tissue in the conventional outflow pathway and the neuroinflammation process ...
Stefania Vernazza +4 more
openaire +2 more sources
Primary open-angle glaucoma genes [PDF]
A substantial fraction of glaucoma has a genetic basis. About 5% of primary open angle glaucoma (POAG) is currently attributed to single-gene or Mendelian forms of glaucoma (ie glaucoma caused by mutations in myocilin or optineurin). Mutations in these genes have a high likelihood of leading to glaucoma and are rarely seen in normal subjects.
openaire +2 more sources
Primary Open Angle Glaucoma [PDF]
Primary open-angle glaucoma is a progressive chronic optic neuropathy, typically bilateral, that occurs after the age of 40 years. It is the second leading cause of irreversible blindness in the world. Primary open-angle glaucoma corresponds to a progressive loss of retinal ganglion cell characterized by an excavation of the optic disc associated with ...
S, Bertaud +3 more
openaire +3 more sources
Biomarkers of primary open-angle glaucoma [PDF]
Primary open-angle glaucoma (POAG) is a primary neuronal disease of the optic nerve without a definable cause, and is often associated with increased intraocular pressure. Worldwide, POAG is the second leading cause of blindness; there are 45 million people today with POAG and bilateral blindness is present in 4.5 million of these.
Paul A, Knepper +2 more
openaire +2 more sources
Biomarkers in primary open angle glaucoma
AbstractGlaucoma, a leading cause of blindness worldwide, is currently defined as a disturbance of the structural or functional integrity of the optic nerve that causes characteristic atrophic changes in the optic nerve, which may lead to specific visual field defects over time.
Kokotas, H. +6 more
openaire +3 more sources
Effect of myricetin on primary open-angle glaucoma [PDF]
Abstract Background Primary open angle glaucoma (POAG) is the most common form of glaucoma, with a multifactorial etiology that results in retinal ganglion cell death and loss of vision. In this study, we assessed the effects of myricetin on the trabecular meshwork cells in POAG.
Yang Qing, Li Ying, Luo Lin
openaire +3 more sources
Hypertension in Primary Open Angle Glaucoma
Introduction: The impact of vascular factors in POAG is well known and controversial. Some reports have shown high blood pressure in POAG, some low systolic blood pressure and some described no difference in blood pressure between POAG and controls. However decreased ocular perfusion pressure was found in most of the studies.
Suprada Pokharel +2 more
openaire +5 more sources

