Results 31 to 40 of about 55,410 (225)

Mitochondrial damage in the trabecular meshwork occurs only in primary open-angle glaucoma and in pseudoexfoliative glaucoma.

PLoS ONE, 2011
BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti, Mariagrazia Longobardi, Cristina Cartiglia, Sergio Claudio Saccà   +3 more
doaj   +1 more source

Detection of glaucoma in a cohort of chinese subjects with systemic hypertension [PDF]

, 2013
Purpose. To determine the presence and type of glaucoma in a cohort of adult Chinese subjects with systemic hypertension. Methods. This prospective cohort study included 200 hypertensive Chinese adults aged >40 years old who underwent screening via ...
Chan, J, Gangwani, RA, Kwong, A, Lai, JSM, Lee, J   +4 more
core   +1 more source

What was Glaucoma Called Before the 20th Century? [PDF]

, 2015
Glaucoma involves a characteristic optic neuropathy, often with elevated intraocular pressure. Before 1850, poor vision with a normal eye appearance, as occurs in primary open-angle glaucoma, was termed amaurosis, gutta serena, or black cataract.
Bermudez, Dennis, Giliberti, Francesca M., Leffler, Christopher T., Schwartz, Stephen G., Young, Matthew T.   +4 more
core   +3 more sources

Primary open-angle glaucoma

Delta Journal of Ophthalmology, 2022
Aim The aim of this study was to show if primary open-angle glaucoma (POAG) is associated with structural neurodegenerative changes along the visual pathway. Patients and methods The patients included in the study were divided into two groups: group 1 (200 patients having POAG) and ...
Ahmed A. Alhagaa, Rehab M. Habib
openaire   +1 more source

The p53 codon 72 PRO/PRO genotype may be associated with initial central visual field defects in Caucasians with primary open angle glaucoma [PDF]

, 2012
Background: Loss of vision in glaucoma is due to apoptotic retinal ganglion cell loss. While p53 modulates apoptosis, gene association studies between p53 variants and glaucoma have been inconsistent.
Alex W. Hewitt, Anneke I. den. Hollander, Anthony Realini, Bao Jian Fan, Colm O’Brien, Dan Yi Wang, David A. Mackey, David P. Dimasi, Dayse R. Figueiredo Sena, Jamie E. Craig, Janey L. Wiggs, Jonathan L. Haines, Louis R. Pasquale   +12 more
core   +5 more sources

Molecular genetics of primary open-angle glaucoma

Indian Journal of Ophthalmology, 2023
Glaucoma is a series of linked optic diseases resulting in progressive vision loss and total blindness due to the acquired loss of retinal ganglion cells.
Manoj Yadav, Aarti Bhardwaj, Anshu Yadav, Rima Dada, Mukesh Tanwar   +4 more
doaj   +1 more source

Rates of macular volume changes in different stages and courses of primary open-angle glaucoma

Journal of Ophthalmology
Purpose: To examine macular volume changes as assessed by optical coherence tomography (OCT) and rates of these changes in different stages and courses of primary open-angle glaucoma (POAG).
M. V. Panchenko, O. M. Honchar, H. Yu. Panchenko, I. V. Kitchenko   +3 more
doaj   +1 more source

Time‐course characterization of intraocular pressure in murine steroid‐induced ocular hypertension: Effects of route, schedule, and concentration

Animal Models and Experimental Medicine, EarlyView.
Steroid‐induced ocular hypertension is a useful mouse model for glaucoma, but published work rarely quantifies how route, dose, and schedule shape the intraocular pressure (IOP) time‐course—hindering reproducibility and forcing labs to pilot protocols.
Nicholas Y. Q. Tan, Sai Bo Bo Tun, Hla Myint Htoon, Veluchamy Amutha Barathi, Tina T. Wong   +4 more
wiley   +1 more source

GWAS-by-subtraction reveals an IOP-independent component of primary open angle glaucoma

Nature Communications
The etiology of primary open angle glaucoma is constituted by both intraocular pressure-dependent and intraocular pressure-independent mechanisms.
Yu Huang, Denis Plotnikov, Huan Wang, Danli Shi, Cong Li, Xueli Zhang, Xiayin Zhang, Shulin Tang, Xianwen Shang, Yijun Hu, Honghua Yu, Hongyang Zhang, Jeremy A. Guggenheim, Mingguang He   +13 more
doaj   +1 more source

Association between hypertriglyceridemia and open angle glaucoma: A case report

Indian Journal of Ophthalmology, 2019
Hypertriglyseridemia is a metabolic disorder that can cause vascular dysfucntion and be causally associated with glaucoma. Herein we present the case of a 16-year-old boy with hypertriglyseridemia with open-angle glaucoma.
Mayuri Bakulesh Khamar, Arpita P Sthapak, D Vijayevarshcini, Priyanka M Patel   +3 more
doaj   +1 more source