Results 21 to 30 of about 178,746 (299)

Stress induced aging in mouse eye

Aging Cell, Volume 21, Issue 12, December 2022., 2022
Skowronska‐Krawczyk and colleagues describe the transcriptional and epigenetic changes happening in aging retina. They also show that upon stress such as intraocular pressure elevation in the eye, retinal tissue undergoes epigenetic and transcriptional changes similar to natural aging.
Qianlan Xu, Cezary Rydz, Viet Anh Nguyen Huu, Lorena Rocha, Claudia Palomino La Torre, Irene Lee, William Cho, Mary Jabari, John Donello, David C. Lyon, Robert T. Brooke, Steve Horvath, Robert N. Weinreb, Won‐Kyu Ju, Andrzej Foik, Dorota Skowronska‐Krawczyk   +15 more
wiley   +1 more source

Association Between PM2.5 Exposure Level and Primary Open-Angle Glaucoma in Taiwanese Adults: A Nested Case–control Study

International Journal of Environmental Research and Public Health, 2021
Primary open-angle glaucoma (POAG) is the most common type of glaucoma. However, little is known about POAG in adults and exposure to air pollution.
Han-Yin Sun, Ci-Wen Luo, Yun-Wei Chiang, Kun-Lin Yeh, Yi-ching Li, Yung-Chung Ho, Shiuan-Shinn Lee, Wen-Ying Chen, Chun-Jung Chen, Y. Kuan   +9 more
semanticscholar   +1 more source

Long-term Results of the PRESERFLO MicroShunt in Patients With Primary Open-angle Glaucoma From a Single-center Nonrandomized Study

Journal of glaucoma, 2020
Precis: The MicroShunt was implanted in 23 patients with primary open-angle glaucoma (POAG) in a feasibility study. Reductions in intraocular pressure (IOP) and medications were sustained for up to 5 years with no long-term sight-threatening adverse ...
J. Batlle, A. Corona, Rachel Albuquerque
semanticscholar   +1 more source

The Ocular Hypertension Treatment Study: a randomized trial determines that topical ocular hypotensive medication delays or prevents the onset of primary open-angle glaucoma.

A M A Archives of Ophthalmology, 2002
BACKGROUND Primary open-angle glaucoma (POAG) is one of the leading causes of blindness in the United States and worldwide. Three to 6 million people in the United States are at increased risk for developing POAG because of elevated intraocular pressure (
R. Fechtner, Nicholas Karunaratne, Albert S. Khoury, T. Realini, Jianming Ren, Michelle Robison, George Shafranov, Gilbert Sussman, Mike Roy Willman, Thomas W. Uihlein, E. E. Hartmann, Anna A. Norris, Melissa X. Perez, M. Piccone, Anna Purna Singh, Andrea V. Gray   +15 more
semanticscholar   +1 more source

elastography in primary open-angle glaucoma [PDF]

, 2016
Objective: The aim of this study was to compare sonoelastographic findings in the retina-choroid-sclera (RCS) complex and vitreous in glaucomatous and healthy eyes.Methods: For this cross-sectional comparative study, 20 patients with primary open-angle ...
Agladioglu, K, Kasikci, SA, Kiroglu, Y, Pekel, G, Yagci, R   +4 more
core   +2 more sources

The Ocular Hypertension Treatment Study: baseline factors that predict the onset of primary open-angle glaucoma.

A M A Archives of Ophthalmology, 2002
BACKGROUND The Ocular Hypertension Treatment Study (OHTS) has shown that topical ocular hypotensive medication is effective in delaying or preventing the onset of primary open-angle glaucoma (POAG) in individuals with elevated intraocular pressure ...
M. Gordon, J. Beiser, J. Brandt, D. Heuer, E. Higginbotham, Chris A. Johnson, J. Keltner, J. Miller, R. Parrish, M. Wilson, M. Kass   +10 more
semanticscholar   +1 more source

Early diagnosis and research of high myopia with primary open angle glaucoma [PDF]

, 2014
People with high myopia are high risk populations to have primary open angle glaucoma. Clinically, we found that patients with primary open angle glaucoma and high myopia is closely related.
Guo-Ping Kuang, Yan Guo
core   +1 more source

Microstructural Visual Pathway White Matter Alterations in Primary Open-Angle Glaucoma:A Neurite Orientation Dispersion and Density Imaging Study [PDF]

, 2022
BACKGROUND AND PURPOSE: DTI studies of patients with primary open-angle glaucoma have demonstrated that glaucomatous degeneration is not confined to the retina but involves the entire visual pathway.
Carvalho, J., Cornelissen, F. W., Haykal, S., Invernizzi, A., Jansonius, N. M.   +4 more
core   +1 more source

Mitochondrial Damage in the Trabecular Meshwork Occurs Only in Primary Open-Angle Glaucoma and in Pseudoexfoliative Glaucoma [PDF]

, 2011
Open-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
A Bakunowicz-Lazarczyk, A Izzotti, A Izzotti, A Izzotti, A Takahashi, A Tawara, A Tawara, AG Konstas, Alberto Izzotti, Alfred Lewin, AS Shifera, AW Linnane, B Ramamurthy, B Van Houten, C Brenner, C Krieger, CG Murphy, Cristina Cartiglia, CY Pang, DR Anderson, E Maul, FM Yakes, G Li, GO Waring, HC Lee, I Trounce, J Caprioli, J Gottanka, JA Alvarado, JA Alvarado, JA Alvarado, JA Alvarado, JP Ehlers, K Sas, KK Abu-Amero, Mariagrazia Longobardi, MB Shields, MB Shields, N Furuyoshi, N Gupta, N Tane, NS Hamblet, P Brusini, R Ritch, R Ritch, S Di Mauro, SC Saccà, SC Saccà, SC Saccà, SC Saccà, Sergio Claudio Saccà, TC Yen, U Schlotzer-Schrehardt, VW Liu, Y He, YH Wei   +55 more
core   +3 more sources

Prevalence and determinants of glaucoma : an epidemiologic approach (The Rotterdam Study) [PDF]

, 1995
Glaucoma is an eye disease characterized by damage to the optic nerve head and related visual field defects, often accompanied by elevated intraocular pressure. Glaucoma is an important cause of blindness, particularly in the elderly.
Dielemans, I. (Ida)
core   +7 more sources