Results 31 to 40 of about 91,310 (286)

MicroRNAs as biomarkers in glaucoma and potential therapeutic targets

Neural Regeneration Research, 2022
Glaucoma is a neurodegenerative disease in which optic nerve damage and visual field defects occur. It is a leading cause of irreversible blindness. Its pathogenesis is largely unknown although several risk factors have been identified, with an increase ...
Bridget Martinez, Philip V Peplow
doaj   +1 more source

Effect of Glaucoma on Corneal Endothelium [PDF]

Egyptian Journal of Medical Research, 2021
Background: Glaucoma is a group of diseases characterized by a specific pattern of optic nerve neuropathy and retinopathy which is permenant. There is increasing evidence of glaucoma-associated corneal endothelial changes.
Hazem Effat Abd El-Ghany Mohammad Haroon, Asmaa Mohamed Samir, Haytham Ibrahim Ibrahim El-Shawaf, Muller Victor Shaker   +3 more
doaj   +1 more source

Asymmetric Patterns of Visual Field Defect in Primary Open-Angle and Primary Angle-Closure Glaucoma [PDF]

, 2018
Purpose: To compare the hemifield asymmetry of visual field (VF) loss in primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) across all severity levels. Methods: A total of 522 eyes of 327 patients with POAG (mean age ± SD, 54.
Asaoka, R, Fujino, Y, Garway-Heath, D, Murata, H, Sakai, H, Weinreb, R, Yousefi, S   +6 more
core   +1 more source

Genome-wide analyses identify 68 new loci associated with intraocular pressure and improve risk prediction for primary open-angle glaucoma

Nature Genetics, 2018
Glaucoma is the leading cause of irreversible blindness globally1. Despite its gravity, the disease is frequently undiagnosed in the community2. Raised intraocular pressure (IOP) is the most important risk factor for primary open-angle glaucoma (POAG)3,4.
A. Khawaja, J. C. Cooke Bailey, N. Wareham, R. Scott, Mark J. Simcoe, R. Igo, Yeunjoo E. Song, R. Wojciechowski, Ching-Yu Cheng, P. Khaw, L. Pasquale, J. Haines, P. Foster, J. Wiggs, C. Hammond, P. Hysi   +15 more
semanticscholar   +1 more source

Visual field loss and vision-related quality of life in the Italian Primary Open Angle Glaucoma Study. [PDF]

, 2018
The aim of this study was to examine the relationship between visual field (VF) loss, vision-related quality of life (QoL) and glaucoma-related symptoms in a large cohort of primary open angle glaucoma (POAG) patients.
Galli, Fabio, Hollander, Lital, Italian Study Group on QoL in Glaucoma, Katsanos, Andreas, Oddone, Francesco, Poli, Davide, Quaranta, Luciano, Riva, Ivano, Rulli, Eliana, Torri, Valter, Weinreb, Robert N   +10 more
core   +2 more sources

Two-year results of a multicenter study of the ab interno gelatin implant in medically uncontrolled primary open-angle glaucoma

Graefe's Archive for Clinical and Experimental Ophthalmology, 2019
PurposeTo evaluate the effectiveness of an ab interno subconjunctival gelatin implant as primary surgical intervention in reducing intraocular pressure (IOP) and IOP-lowering medication count in medically uncontrolled moderate primary open-angle glaucoma
H. Reitsamer, Chelvin C A Sng, Vanessa Vera, Markus Lenzhofer, K. Barton, I. Stalmans, for the Turkish Erm Study Group   +6 more
semanticscholar   +1 more source

Progression from ocular hypertension to visual field loss in the English hospital eye service [PDF]

, 2020
Background There are more than one million National Health Service visits in England and Wales each year for patients with glaucoma or ocular hypertension (OHT).
Azuara-Blanco, A., Bryan, S. R., Crabb, D. P., Kelly, S. R., Khawaja, A. P., Sparrow, J. M.   +5 more
core   +2 more sources

Tear and aqueous humour cytokine profile in primary open-angle glaucoma.

Acta ophthalmologica, 2020
PURPOSE To evaluate the concentrations of pro-inflammatory cytokines in tear and aqueous humour of patients with primary open-angle glaucoma (POAG), relative to healthy controls.
B. Burgos-Blasco, B. Vidal-Villegas, F. Saénz-Francés, L. Morales-Fernández, L. Perucho‐González, J. García-Feijóo, J. Martínez-de-la-Casa   +6 more
semanticscholar   +1 more source

Mitochondrial damage in the trabecular meshwork occurs only in primary open-angle glaucoma and in pseudoexfoliative glaucoma.

PLoS ONE, 2011
BackgroundOpen-angle glaucoma appears to be induced by the malfunction of the trabecular meshwork cells due to injury induced by oxidative damage and mitochondrial impairment.
Alberto Izzotti, Mariagrazia Longobardi, Cristina Cartiglia, Sergio Claudio Saccà   +3 more
doaj   +1 more source

Long-term 24-hour intraocular pressure control with travoprost monotherapy in patients with primary open-angle glaucoma [PDF]

, 2014
The aim of the study was to evaluate the long-term 24-hour intraocular pressure (IOP) efficacy of travoprost monotherapy in primary open-angle glaucoma ...
Biagioli, Elena, Centofanti, M, Floriani, Irene, Katsanos, Andreas, Konstas, Anastasios, Quaranta, Luciano, Riva, Ivano   +6 more
core   +1 more source