Results 211 to 220 of about 4,572,451 (270)

The role of RAD51 regulators and variants in primary ovarian insufficiency, endometriosis, and polycystic ovary syndrome. [PDF]

NAR Mol Med
Witham M, Hengel SR.
europepmc   +1 more source

Targeting the CD47–SIRPα phagocytic checkpoint in cancer: Biology, translational opportunities, and next‐generation therapeutic strategies

Smart Molecules, EarlyView.
The CD47–SIRPα axis has emerged as a critical innate immune checkpoint that suppresses macrophage‐mediated phagocytosis through a canonical “don't eat me” signal and enables tumor immune evasion. We comprehensively summarize the structural and biological features of CD47 and the molecular mechanisms underlying CD47‐mediated regulation of phagocytosis ...
Ruimei Zhou, Lingjie Jing, Jianping Zhang, Cheng Guo, Quanjun Yang   +4 more
wiley   +1 more source

Women's healthcare providers' knowledge and practices surrounding fragile-X associated primary ovarian insufficiency (FXPOI). [PDF]

J Assist Reprod Genet
Singleton AL, Hipp HS, Ali N, Poteet B, Allen EG.   +4 more
europepmc   +1 more source

Diagnostic imaging of adnexal lesions in pregnancy: systematic review

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objective To describe the imaging features of adnexal lesions during pregnancy and assess the performance of current models for the risk assessment of such lesions. Methods This was a PROSPERO‐registered systematic review including studies published from inception to 1 August 2025 and was performed as per Preferred Reporting Systems for ...
N. Cooper, N. Kotecha, A. Novak, J. Barcroft, J. Yazbek, C. Landolfo, M. Al‐Memar, D. Timmerman, S. Saso, T. Bourne   +9 more
wiley   +1 more source

Response to Letter to the Editor: Breast Cancer is Increased in Women With Primary Ovarian Insufficiency.

J Clin Endocrinol Metab
Allen-Brady K, Johnstone EB, Welt CK.
europepmc   +1 more source

Identifying therapeutic targets for primary ovarian insufficiency through integrated genomic analyses. [PDF]

J Ovarian Res
Du H, Zeng P, Liu X, Zhang J, Huang Z.
europepmc   +1 more source

Peptide‐directed nanovehicles enabling tumor‐selective ROS amplification and antitumor immunity

VIEW, EarlyView.
Cancer cells are vulnerable to oxidative stress, yet exploit immune tolerance to escape destruction. In contrast, their metabolic profile is markedly altered to support rapid proliferation, accompanied by elevated production of reactive oxygen species (ROS).
Manuela Calin, Galyna Bila, Ileana Manduteanu, Rostyslav Bilyy   +3 more
wiley   +1 more source

Primary ovarian insufficiency consequence of autoimmune diseases: a bidirectional two-sample Mendelian randomization study. [PDF]

Front Endocrinol (Lausanne)
Du Y, Hu Y, Sheng Y, Zhu T, Liu S, Ding H, Guan Y.   +6 more
europepmc   +1 more source

Nanobodies as next‐generation targeting platforms: From discovery technologies to translational biomedicine

VIEW, EarlyView.
Nanobodies, derived from the variable domains of camelid heavy‐chain‐only antibodies, have emerged as transformative biomedical tools due to their nanoscale size, exceptional stability, and unique capacity to recognize cryptic epitopes. This review provides a comprehensive overview of the field, outlining the structural and biochemical features of ...
Zhenrui Ye, Xianyang Li, Meixiao Zhan
wiley   +1 more source

Risk of Cancer With Hormone Replacement Therapy: A Narrative Review

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Hormone replacement therapy (HRT) remains the cornerstone of menopausal symptom management, effectively alleviating vasomotor symptoms and genitourinary syndrome, whilst mitigating long‐term risks such as osteoporosis. However, despite an increasing body of evidence on the relative safety of HRT, earlier studies that demonstrated an increased ...
Gabriella Yongue, Zachary Nash, Vikram Talaulikar, Shibani Nicum   +3 more
wiley   +1 more source