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Primary ovarian insufficiency: a toolkit for the busy clinician.
Menopause, 2023Primary ovarian insufficiency (sometimes known as premature ovarian insufficiency) is a result of loss of ovarian follicular activity before the age of 40 years.
Ekta Kapoor
semanticscholar +1 more source
2021
Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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Molecular Nutrition & Food Research
SCOPE Premature ovarian insufficiency (POI) is a common female infertility problem, with its pathogenesis remains unknown. The NOD-like receptor family pyrin domain-containing 3 (NLRP3)-mediated pyroptosis has been proposed as a possible mechanism in POI.
Ke Liu +11 more
semanticscholar +1 more source
SCOPE Premature ovarian insufficiency (POI) is a common female infertility problem, with its pathogenesis remains unknown. The NOD-like receptor family pyrin domain-containing 3 (NLRP3)-mediated pyroptosis has been proposed as a possible mechanism in POI.
Ke Liu +11 more
semanticscholar +1 more source
The global prevalence of primary ovarian insufficiency and early menopause: a meta-analysis
Climacteric, 2019Objective: The aim of this study was to estimate the global prevalence of primary ovarian insufficiency (POI) and early menopause (EM). Methods: A comprehensive literature search was performed in several databases to retrieve relevant English articles ...
S. Golezar +4 more
semanticscholar +1 more source
Genitourinary symptoms and sexual function in women with primary ovarian insufficiency
ClimactericObjective There are limited studies on urogenital symptoms in women who experience menopause before the age of 40 years due to primary ovarian insufficiency (POI) or bilateral oophorectomy (surgical POI).
J. Blümel +13 more
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Bone Health in Primary Ovarian Insufficiency
Seminars in Reproductive Medicine, 2011The etiology of primary ovarian insufficiency (POI) may be genetic, autoimmune, or iatrogenic. Genetic conditions include 45,X, 46,XX and 46,XY POI, and POI associated with galactosemia and FMR premutations. Women with autoimmune polyglandular syndromes 1 and 2 may develop autoimmune POI, as may those who receive chemotherapy or radiotherapy ...
Rose, Marino, Madhusmita, Misra
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The Journal of Clinical Endocrinology & Metabolism, 1968
ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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Primary Amenorrhea and Premature Ovarian Insufficiency
Endocrinology and Metabolism Clinics of North AmericaThis review focuses on primary amenorrhea and primary/premature ovarian insufficiency due to hypergonadotropic hypogonadism. Following a thoughtful, thorough evaluation, a diagnosis can usually be discerned. Pubertal induction and ongoing estrogen replacement therapy are often necessary.
Svetlana A, Yatsenko +2 more
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Primary ovarian insufficiency in the adolescent
Current Opinion in Obstetrics & Gynecology, 2013To raise awareness about the importance of early diagnosis of primary ovarian insufficiency (POI) in the adolescent.Menstrual cycle irregularity or amenorrhea in the adolescent has historically been treated with oral contraceptives or ignored, with no evaluation done to determine the cause. However, it is now becoming clear that the health consequences
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