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2017
Premature ovarian insufficiency (POI) can be defined as a cessation of ovarian function in women younger than 40 years old and is linked to the development of hypergonadotropic hypogonadism. The hypogonadism clinically presents as amenorrhea, which sometimes is preceded by oligomenorrhea and decreased circulating estradiol levels.
Podfigurny, Agnieszka +4 more
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Premature ovarian insufficiency (POI) can be defined as a cessation of ovarian function in women younger than 40 years old and is linked to the development of hypergonadotropic hypogonadism. The hypogonadism clinically presents as amenorrhea, which sometimes is preceded by oligomenorrhea and decreased circulating estradiol levels.
Podfigurny, Agnieszka +4 more
+4 more sources
Current Obstetrics and Gynecology Reports, 2014
Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Primary ovarian insufficiency in the adolescent
Current Opinion in Obstetrics & Gynecology, 2013To raise awareness about the importance of early diagnosis of primary ovarian insufficiency (POI) in the adolescent.Menstrual cycle irregularity or amenorrhea in the adolescent has historically been treated with oral contraceptives or ignored, with no evaluation done to determine the cause. However, it is now becoming clear that the health consequences
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2021
Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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The Journal of Clinical Endocrinology & Metabolism, 1968
ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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Bone Health in Primary Ovarian Insufficiency
Seminars in Reproductive Medicine, 2011The etiology of primary ovarian insufficiency (POI) may be genetic, autoimmune, or iatrogenic. Genetic conditions include 45,X, 46,XX and 46,XY POI, and POI associated with galactosemia and FMR premutations. Women with autoimmune polyglandular syndromes 1 and 2 may develop autoimmune POI, as may those who receive chemotherapy or radiotherapy ...
Rose, Marino, Madhusmita, Misra
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Update on primary ovarian insufficiency in adolescents
Current Opinion in Pediatrics, 2015We provide an overview of new insights into the genetic causes of primary ovarian insufficiency (POI) and address the challenges faced by clinicians who care for adolescents with this condition.In most cases, the cause of POI remains a mystery after appropriate clinical testing has been completed.
Catherine M, Gordon +2 more
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Primary Ovarian Insufficiency: Current Concepts
Southern Medical Journal, 2017A potential consequence of chemotherapy is the destruction of oocytes, resulting in primary ovarian insufficiency (POI) in young patients; this often results in secondary amenorrhea and necessitates hormone replacement therapy. Regardless of the etiology of POI, the chance of pregnancy is low in this patient population. Given the extent to which oocyte
Gretchen, Collins +3 more
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Etiologies of Primary Ovarian Insufficiency
2016Primary ovarian insufficiency (POI) is a subclass of ovarian dysfunction in which the resting pool of primordial follicles is prematurely exhausted. It occurs through two major mechanisms: a pathologic process that causes follicle dysfunction or development of an inadequate initial pool of primordial follicles during embryogenesis.
Nastaran Foyouzi +2 more
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Primary Amenorrhea and Premature Ovarian Insufficiency
Endocrinology and Metabolism Clinics of North AmericaThis review focuses on primary amenorrhea and primary/premature ovarian insufficiency due to hypergonadotropic hypogonadism. Following a thoughtful, thorough evaluation, a diagnosis can usually be discerned. Pubertal induction and ongoing estrogen replacement therapy are often necessary.
Svetlana A, Yatsenko +2 more
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