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Current Obstetrics and Gynecology Reports, 2014
Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Primary ovarian insufficiency (POI) is a syndrome of amenorrhoea, sex steroid deficiency, and elevated gonadotropins in a woman aged more than two standard deviations below the mean age for menopause estimated for her reference population. In practical terms, it occurs spontaneously in 1 % of women before the age of 40 years. Apart from idiopathic POI,
Rodney J. Baber, Michele Kwik
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Molecular Nutrition & Food Research
SCOPE Premature ovarian insufficiency (POI) is a common female infertility problem, with its pathogenesis remains unknown. The NOD-like receptor family pyrin domain-containing 3 (NLRP3)-mediated pyroptosis has been proposed as a possible mechanism in POI.
Ke Liu +11 more
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SCOPE Premature ovarian insufficiency (POI) is a common female infertility problem, with its pathogenesis remains unknown. The NOD-like receptor family pyrin domain-containing 3 (NLRP3)-mediated pyroptosis has been proposed as a possible mechanism in POI.
Ke Liu +11 more
semanticscholar +1 more source
Primary Ovarian Insufficiency: Current Concepts
Southern Medical Journal, 2017A potential consequence of chemotherapy is the destruction of oocytes, resulting in primary ovarian insufficiency (POI) in young patients; this often results in secondary amenorrhea and necessitates hormone replacement therapy. Regardless of the etiology of POI, the chance of pregnancy is low in this patient population. Given the extent to which oocyte
Gretchen, Collins +3 more
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Primary ovarian insufficiency: autoimmune causes
Current Opinion in Obstetrics & Gynecology, 2010To review the pathogenesis of premature ovarian insufficiency due to steroid cell autoimmunity (SCA-POI).Autoimmune oophoritis is characterized by a selective mononuclear cell infiltration into the theca layer of large, antral follicles, with earlier stage follicles consistently free of lymphocytic infiltration.
A. La Marca +5 more
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Reproductive Biomedicine Online, 2023
RESEARCH QUESTION Is there a protective effect of the humanin derivative [Gly14]-humanin (HNG) on a D-gal-induced mouse model of primary ovarian insufficiency (POI), and what is the underlying mechanism?
Jin Huang +6 more
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RESEARCH QUESTION Is there a protective effect of the humanin derivative [Gly14]-humanin (HNG) on a D-gal-induced mouse model of primary ovarian insufficiency (POI), and what is the underlying mechanism?
Jin Huang +6 more
semanticscholar +1 more source
2021
Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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Primary ovarian insufficiency (POI) is defined as the development of primary (hypergonadotropic) hypogonadism before the age of 40 years. The diagnostic criteria of POI are irregular menses in women before the age of 40 years in association with follicle-stimulating hormone level in the postmenopausal range.
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The global prevalence of primary ovarian insufficiency and early menopause: a meta-analysis
Climacteric, 2019Objective: The aim of this study was to estimate the global prevalence of primary ovarian insufficiency (POI) and early menopause (EM). Methods: A comprehensive literature search was performed in several databases to retrieve relevant English articles ...
S. Golezar +4 more
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Primary ovarian insufficiency: a toolkit for the busy clinician.
Menopause, 2023Primary ovarian insufficiency (sometimes known as premature ovarian insufficiency) is a result of loss of ovarian follicular activity before the age of 40 years.
Ekta Kapoor
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Bone Health in Primary Ovarian Insufficiency
Seminars in Reproductive Medicine, 2011The etiology of primary ovarian insufficiency (POI) may be genetic, autoimmune, or iatrogenic. Genetic conditions include 45,X, 46,XX and 46,XY POI, and POI associated with galactosemia and FMR premutations. Women with autoimmune polyglandular syndromes 1 and 2 may develop autoimmune POI, as may those who receive chemotherapy or radiotherapy ...
Rose, Marino, Madhusmita, Misra
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The Journal of Clinical Endocrinology & Metabolism, 1968
ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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ABSTRACT A patient is described who developed idiopathic hypoparathyroidism at age 3, primary ovarian failure at age 15, and primary adrenocortical failure at age 17. The primary nature of the ovarian insufficiency is indicated by the finding on several occasions of elevated urinary gonadotropin.
J E, Golonka, A D, Goodman
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