Results 121 to 130 of about 7,915,710 (337)

Emerging role of ARHGAP29 in melanoma cell phenotype switching

Molecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster, Melanie Kappelmann‐Fenzl, Anja Katrin Bosserhoff, Nicole Rachinger   +3 more
wiley   +1 more source

Tobacco attributable Disability-Adjusted Life Years (DALYs) burden in Poland and Hungary: The role of women

Tobacco Induced Diseases, 2021
Paweł Koczkodaj, Joanna Didkowska
doaj   +1 more source

What do dentists do and earn? An exploratory analysis of French dentists with a focus on primary care teams

BMC Primary Care
Access to dental care in France faces two main barriers: high out-of-pocket costs and a widely uneven distribution of dentists. Multiprofessional primary care groups (MPCGs) are currently in development to improve primary care efficiency and enhance the ...
Anne-Charlotte Bas, Matthieu Cassou, Carine Franc   +2 more
doaj   +1 more source

Primary prevention of cardiovascular disease with a Mediterranean diet.

New England Journal of Medicine, 2013
R. Estruch, E. Ros, J. Salas‐Salvadó, M. Covas, D. Corella, F. Arós, E. Gómez-Gracia, V. Ruíz-Gutiérrez, M. Fiol, J. Lapetra, R. Lamuela-Raventós, L. Serra-Majem, X. Pintó, J. Basora, M. Muñoz, J. Sorlí, J. A. Martínez, M. Martínez-González   +17 more
semanticscholar   +1 more source

Status of Infection Prevention and Control in Tanzanian Primary Health Care Facilities: Learning From Star Rating Assessment

, 2020
Erick S. Kinyenje, Joseph C. Hokororo, Eliudi S. Eliakimu, Talhiya A. Yahya, Bernard Mbwele, Mohamed Mohamed, Gideon Kwesigabo   +6 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Prevention of Second Primary Tumors with Isotretinoin in Squamous-Cell Carcinoma of the Head and Neck [PDF]

, 1990
Waun Ki Hong, S. M. Lippman, Loretta M. Itri, Daniel D. Karp, Jin S. Lee, Robert M. Byers, Stimson P. Schantz, Alan Kramer, R. Lotan, Lester J. Peters, Isaiah W. Dimery, Bethany L. Wagner, Helmuth Goepfert   +12 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source

Obstructive sleep apnea and the severity of coronary artery disease

Caspian Journal of Internal Medicine, 2018
Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension.
Ali Vasheghani-Farahani, Fatemeh Kazemnejad, Khosro Sadeghniiat-Haghighi, Soleil Saadat, Parya Tavakoli poor, Tahereh Yazdani, Mohammad Alidoosti, Vahid Ghasem Amooeian, Haleh Ashraf   +8 more
doaj  

Protocol for sampling multidrug-resistant bacteria using artificial plastic substrates in aquatic ecosystems

STAR Protocols
Summary: Artificial plastic substrates (APSs) consist of four plastic polymers that work as traps for pathogenic bacteria and facilitate their sampling and detection.
Ifra Ferheen, Roberto Spurio, Stefania Marchggiani   +2 more
doaj   +1 more source