Results 121 to 130 of about 7,735,427 (345)

2019 ACC/AHA Guideline on the Primary Prevention of Cardiovascular Disease: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines.

Journal of the American College of Cardiology, 2019
D. Arnett, R. Blumenthal, Michelle A. Albert, E. Michos, Andrew B. Buroker, M. Miedema, Z. Goldberger, D. Muñoz, E. Hahn, Sidney C. Smith, C. D. Himmelfarb, S. Virani, A. Khera, K. Williams, D. Lloyd‐Jones, J. Yeboah, J. McEvoy, B. Ziaeian, Aha Task Force Members, P. O'Gara, J. Beckman, Glenn N. Levine, Immediate Past Chair, S. Al‐Khatib, M. Hlatky, K. Birtcher, J. Ikonomidis, J. Cigarroa, J. Joglar, A. Deswal, L. Mauri, L. Fleisher, M. Piano, Federico Gentile, B. Riegel, D. Wijeysundera   +35 more
semanticscholar   +1 more source

Olaparib synergy screen reveals Exemestane induces replication stress in triple‐negative breast cancer

Molecular Oncology, EarlyView.
Screening 166 FDA‐approved anticancer drugs identifies the aromatase inhibitor Exemestane as a synergistic partner of PARP inhibitor Olaparib in BRCA‐proficient triple‐negative breast cancer. Exemestane induces ROS‐mediated replication stress, enhancing DNA damage and apoptosis alongside Olaparib.
Nur Aininie Yusoh, Liping Su, Suet Lin Chia, Xiaohe Tian, Haslina Ahmad, Martin R. Gill   +5 more
wiley   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Obstructive sleep apnea and the severity of coronary artery disease

Caspian Journal of Internal Medicine, 2018
Background: It has been implicated that obstructive sleep apnea (OSA) is associated with increased risk of cardiovascular disease including stroke, myocardial infarction, coronary artery disease (CAD) and hypertension.
Ali Vasheghani-Farahani, Fatemeh Kazemnejad, Khosro Sadeghniiat-Haghighi, Soleil Saadat, Parya Tavakoli poor, Tahereh Yazdani, Mohammad Alidoosti, Vahid Ghasem Amooeian, Haleh Ashraf   +8 more
doaj  

Protocol for sampling multidrug-resistant bacteria using artificial plastic substrates in aquatic ecosystems

STAR Protocols
Summary: Artificial plastic substrates (APSs) consist of four plastic polymers that work as traps for pathogenic bacteria and facilitate their sampling and detection.
Ifra Ferheen, Roberto Spurio, Stefania Marchggiani   +2 more
doaj   +1 more source

Cancer Prevention in Primary Care Current trends and some prospects for the future - 1 [PDF]

, 1994
Joan Austoker
openalex   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Facilitating prevention in primary care. [PDF]

, 1992
Jeanette Ward
openalex   +1 more source

Primary prevention of cardiovascular disease with a Mediterranean diet.

New England Journal of Medicine, 2013
R. Estruch, E. Ros, J. Salas‐Salvadó, M. Covas, D. Corella, F. Arós, E. Gómez-Gracia, V. Ruíz-Gutiérrez, M. Fiol, J. Lapetra, R. Lamuela-Raventós, L. Serra-Majem, X. Pintó, J. Basora, M. Muñoz, J. Sorlí, J. A. Martínez, M. Martínez-González   +17 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source