Results 81 to 90 of about 7,735,427 (345)

Aspirin for primary prevention of cardiovascular disease: a meta-analysis with a particular focus on subgroups

BMC Medicine, 2019
BackgroundThe role of aspirin in primary prevention of cardiovascular disease (CVD) remains unclear. We aimed to investigate the benefit-risk ratio of aspirin for primary prevention of CVD with a particular focus on subgroups.MethodsRandomized controlled
Georg Gelbenegger, M. Postuła, L. Pecen, S. Halvorsen, M. Lesiak, C. Schoergenhofer, B. Jilma, C. Hengstenberg, J. Siller-Matula   +8 more
semanticscholar   +1 more source

Photosynthesis under far‐red light—evolutionary adaptations and bioengineering of light‐harvesting complexes

FEBS Letters, EarlyView.
Phototrophs evolved light‐harvesting systems adapted for efficient photon capture in habitats enriched in far‐red radiation. A subset of eukaryotic pigment‐binding proteins can absorb far‐red photons via low‐energy chlorophyll states known as red forms.
Antonello Amelii, Edoardo Andrea Cutolo, Daniele Montepietra, Claudia Battarra, Roberto Caferri, Stefano Capaldi, Zeno Guardini, Luca Dall'Osto, Roberto Bassi   +8 more
wiley   +1 more source

A multi-stage approach to support timely health policy decisions during crisis: the fast-track Delphi

BMC Public Health
Background Scientists can play an important role in policymaking by providing evidence and consensual expert opinion on the state of scientific knowledge.
Camille Velarde Crézé, Olivier Duperrex, Luc Lebon, Vincent Faivre, Myriam Pasche, Jacques Cornuz   +5 more
doaj   +1 more source

Integrating smoking cessation counseling into oncology practice — benefits and barriers

Nowotwory
Exposure to tobacco smoke, which contains around 70 carcinogenic components, leads to approximately 8 million deaths worldwide annually. Poland ranks among the top countries with the highest tobacco-related DALY (Disability-Adjusted Life Years) rates ...
Magdalena Cedzyńska, Irena A. Przepiórka   +1 more
doaj   +1 more source

Rad27/FEN1 prevents accumulation of Okazaki fragments and ribosomal DNA copy number changes

FEBS Letters, EarlyView.
The budding yeast Rad27 is a structure‐specific endonuclease. Here, the authors reveal that Rad27 is crucial for maintaining the stability of the ribosomal RNA gene (rDNA) region. Rad27 deficiency leads to the accumulation of Okazaki fragments and changes in rDNA copy number.
Tsugumi Yamaji, Yuko Katayama, Nanase Arata, Mariko Sasaki   +3 more
wiley   +1 more source

Epidemiology of substance and opium use among adult residents of Tehran; a comprehensive report from Tehran cohort study (TeCS)

BMC Psychiatry
Background The prevalence and burden of substance and opium use have increased worldwide over the past decades. In light of rapid population changes in Tehran, we aimed to evaluate the prevalence of opium and other substance use among adult residents in ...
Farzad Masoudkabir, Akbar Shafiee, Amirhossein Heidari, Negin Sadat Hosseini Mohammadi, Kiarash Tavakoli, Arash Jalali, Sepehr Nayebirad, Farshid Alaeddini, Soheil Saadat, Ali Vasheghani-Farahani, Saeed Sadeghian, Vicente Artola Arita, Mohamamdali Boroumand, Abbasali Karimi   +13 more
doaj   +1 more source

Primary prevention of cardiovascular disease: A review of contemporary guidance and literature

JRSM Cardiovascular Disease, 2017
Cardiovascular disease is a significant and ever-growing problem in the United Kingdom, accounting for nearly one-third of all deaths and leading to significant morbidity.
J. Stewart, G. Manmathan, P. Wilkinson
semanticscholar   +1 more source

Mitochondrial fatty acid oxidation is stimulated by red light irradiation

FEBS Letters, EarlyView.
Light at different wavelengths has distinct effects on keratinocyte viability and metabolism. UVA light abrogates metabolic fluxes. Blue and green light have no effect on metabolic fluxes, while red light enhanced oxidative phosphorylation by promoting fatty acid oxidation. Keratinocytes are the primary constituents of sunlight‐exposed epidermis.
Manuel Alejandro Herrera, Camille C. Caldeira da Silva, Maiza Von Denz, Mauricio S. Baptista, Alicia J. Kowaltowski   +4 more
wiley   +1 more source

Role of Statin Therapy in Primary Prevention of Cardiovascular Disease in Elderly Patients

Current Atherosclerosis Reports, 2019
Purpose of ReviewHypercholesterolemia and statin treatment are nowadays common among people older than 75 years, but clinical heterogeneity in this increasing age group is wide, and treatment decisions may differ from those in younger patients. Aim is to
T. Strandberg
semanticscholar   +1 more source

The role of fibroblast growth factors in cell and cancer metabolism

FEBS Letters, EarlyView.
Fibroblast growth factor (FGF) signaling regulates crucial signaling cascades that promote cell proliferation, survival, and metabolism. Therefore, FGFs and their receptors are often dysregulated in human diseases, including cancer, to sustain proliferation and rewire metabolism.
Jessica Price, Chiara Francavilla
wiley   +1 more source