Results 51 to 60 of about 732,851 (264)

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Severe Dietary Energy Restriction for Compensated Cirrhosis Due to Metabolic Dysfunction‐Associated Steatotic Liver Disease: A Randomised Controlled Trial

Journal of Cachexia, Sarcopenia and Muscle
Background Compensated cirrhosis due to metabolic dysfunction‐associated steatotic liver disease (CC‐MASLD) increases morbidity and mortality risk but has no aetiology‐specific treatment.
Dimitrios A. Koutoukidis, Susan A. Jebb, Jeremy W. Tomlinson, Ferenc E. Mozes, Michael Pavlides, Miriam Lacharie, Francesca Saffioti, Paul Aveyard, Jeremy F. Cobbold   +8 more
doaj   +1 more source

Role of magnetic resonance spectroscopy in grading of primary brain tumors

The Egyptian Journal of Radiology and Nuclear Medicine, 2016
Objective: To assess the usefulness of MR spectroscopy (MRS) in grading of primary brain tumors. Methods: MRS was performed in 22 patients with primary brain tumors.
Radwa Kamel Abdel Naser, Afaf Abdel Kader Hassan, Amr Mohamed Shabana, Nagham Nabil Omar   +3 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Quasi-resonant converter with divided resonant capacitor on primary and secondary side

INTELEC 2009 - 31st International Telecommunications Energy Conference, 2009
This paper presents a quasi-resonant converter with divided resonant capacitor on primary and secondary side of the isolation transformer. A conventional quasi-resonant converter using flyback topology can realize soft switching with simple circuit. However, relatively large surge voltage is generated in the switching device.
Hironobu Shiroyama, Hirofumi Matsuo, Yoichi Ishizuka   +2 more
openaire   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source

NONLINEAR PRIMARY RESONANCE OF A CIRCULAR SANDWICH PLATE UNDER STATIC LOAD

Jixie qiangdu, 2021
Based on Reissner’s sandwich plate theory,the nonlinear dynamic equations of the circular sandwich plate under static load are established by using the Hamilton principle.
GUO Wei, DU GuoJun, HU YuDa
doaj  

Primary ovarian leiomyoma: Imaging in a rare entity

Radiology Case Reports, 2020
Primary ovarian leiomyoma is a very rare benign mesenchymal tumor arising from the smooth muscle of walls of ovarian blood vessels. It is usually seen between 20 65 years of age.
Pranav Thombare, MBBS, DMRD, DNB resident, Pooja Chheda, MBBS, DNB resident, Rashmi Parikh, MBBS, DNB, Roshan Shetty, MBBS, MD, DMRD, Mitusha Verma, MBBS, DNB, Deepak Patkar, MBBS, MD   +5 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source