Results 71 to 80 of about 5,924,380 (291)
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
NONLINEAR PRIMARY RESONANCE OF A CIRCULAR SANDWICH PLATE UNDER STATIC LOAD
Jixie qiangdu, 2021 Based on Reissner’s sandwich plate theory,the nonlinear dynamic equations of the circular sandwich plate under static load are established by using the Hamilton principle.
GUO Wei, DU GuoJun, HU YuDa
doaj
Role of magnetic resonance spectroscopy in grading of primary brain tumors
The Egyptian Journal of Radiology and Nuclear Medicine, 2016 Objective: To assess the usefulness of MR spectroscopy (MRS) in grading of primary brain tumors. Methods: MRS was performed in 22 patients with primary brain tumors.
Radwa Kamel Abdel Naser +3 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Evidence informed practice in Primary Education: an unintended but valuable resource
, 2009 This considers the potential of the Teacher Training Resource Bank (TTRB) as a resource for professional development with primary education. Although, the portal was designed with the needs of Teacher Education in mind, the resource has been evaluated as
Blamires, M. +1 more
core
EngAs a key energy-conversion component of tower gravity energy storage systems (T-SGESs), the hoisting structure is susceptible to large-amplitude coupled vibrations when the dominant frequency of a continuous external excitation approaches one of its ...
Kun Cai +7 more
doaj +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
Mode-locked Yb-doped fiber laser ITO-plasmonic metasurface saturable absorber [PDF]
EPJ Web of ConferencesMode-locked fiber lasers are widely used in various applications. While conventional saturable absorbers (SAs), such as semiconductor saturable absorber mirrors, graphene, and carbon nanotubes, have been extensively studied, they still have inherent ...
Kim Ji Su +10 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source