Results 81 to 90 of about 2,008,878 (326)
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
BMC Pediatrics, 2020 Background Lactobacillus spp. play a major role in the development of dental caries. Although effective methods are known for the prevention and management of dental caries, its prevalence of dental caries is increasing amongst school-age children in ...
Dawit Ademe +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
The implementation and impact of the secondary science National Strategy: A single-school case study to explore the changes in classroom teaching styles and the responses of students to these initiatives [PDF]
, 2010 This thesis was submitted for the degree of Doctor of Education and awarded by Brunel University, 7/10/2010.The National Strategy for Science was progressively introduced from 2002 with the intention of providing a clear structure for improved delivery ...
Lloyd-Staples, Chris
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The Role of the Teacher in Primary School Web 2.0 Use
, 2015 Information and communication technologies (ICTs) have become ubiquitous in our society. In particular, 10-12 year old (primary school aged) children report that they increasingly rely upon ICTs for social interaction and for learning (ACMA, 2013).
J. Blannin
semanticscholar +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
Iranian Journal of Psychiatry, 2012 The main purpose of this study was to compare parenting self efficacy between mothers of children with attention deficit-hyperactivity disorder (ADHD) and mothers of normal children.One hundred twenty mothers including 60 mothers of children with ADHD ...
Zahra Gohari +3 more
doaj
Australian and New Zealand Journal of Public Health, 2019 Objective: To investigate the association between hearing impairment (HI) and Year 1 school attendance in Aboriginal children in the Northern Territory (NT) of Australia.
Jiunn-Yih Su +5 more
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
School attendance at basic education in West Africa [PDF]
, 2013 The proportion of children entering primary school at the stipulated age in 2010 in Sub-Saharan Africa was 57%. For the same year, the net attendance ratios for primary and lower secondary education were 76% and 47% respectively.
Kamanda, Mamusu
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