Results 81 to 90 of about 62,620 (348)

Pharmacological interventions for primary sclerosing cholangitis: an attempted network meta-analysis. [PDF]

, 2017
BACKGROUND: Primary sclerosing cholangitis is a chronic cholestatic liver disease that is associated with both hepatobiliary and colorectal malignancies, which can result in liver cirrhosis and its complications. The optimal pharmacological treatment for
Davidson, Brian R, Gurusamy, Kurinchi Selvan, Hawkins, Neil, Saffioti, Francesca, Thorburn, Douglas, Toon, Clare D, Tsochatzis, Emmanuel   +6 more
core   +4 more sources

Fungi participate in the dysbiosis of gut microbiota in patients with primary sclerosing cholangitis

Gut, 2019
Objective Patients with primary sclerosing cholangitis (PSC) were previously shown to display a bacterial gut dysbiosis but fungal microbiota has never been examined in these patients.
S. Lemoinne, Astrid Kemgang, K. Ben Belkacem, M. Straube, Sarah Jégou, C. Corpechot, O. Chazouilleres, C. Housset, H. Sokol   +8 more
semanticscholar   +1 more source

Oral vancomycin solution is superior to capsule in inducing clinical biomarker and endoscopic remission in children with atypical ulcerative colitis

British Journal of Clinical Pharmacology, EarlyView.
Aims Atypical colitis (presenting reverse gradient colitis, backwash ileitis or rectal sparing) is associated with primary sclerosing cholangitis–ulcerative colitis (PSC). Oral vancomycin has been used to manage paediatric atypical colitis with/without confirmed PSC. Different preparations had shown different efficacy.
Laura Räisänen, Fariha Balouch, Claire Reilly, Christopher Burgess, Peter Lewindon   +4 more
wiley   +1 more source

Cholangiocarcinoma in sclerosing cholangitis. The role of liver transplantation [PDF]

, 1989
Our experience with patients who underwent orthotopic liver transplantation for sclerosing cholangitis at the University of Pittsburgh Health Center between March 1980 and March 1988 is reported here.
Iwatsuki, S, Marino, IR, Starzl, TE, Stieber, AC   +3 more
core  

Tacrolimus (FK 506), a Treatment for Primary Sclerosing Cholangitis: Results of an Open‐Label Preliminary Trial [PDF]

, 1995
Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of the liver that is characterized by progressive cholestasis and the development of secondary biliary cirrhosis. There is no widely recognized therapy for this disease, although anti‐
Abu‐Elmagd, K, Carroll, P, Irish, W, McMichael, J, Rodriguez‐Rilo, H, Starzl, TE, Van Thiel, DH   +6 more
core   +1 more source

Monocytes as Potential Mediators of Pathogen‐Induced T‐Helper 17 Differentiation in Patients With Primary Sclerosing Cholangitis (PSC)

Hepatology, 2020
T cells from patients with primary sclerosing cholangitis (PSC) show a prominent interleukin (IL)‐17 response upon stimulation with bacteria or fungi, yet the reasons for this dominant T‐helper 17 (Th17) response in PSC are not clear.
Lilly K. Kunzmann, T. Schoknecht, T. Poch, L. Henze, S. Stein, M. Kriz, I. Grewe, M. Preti, J. Hartl, N. Pannicke, M. Peiseler, M. Sebode, R. Zenouzi, T. Horvatits, Marius Böttcher, B. Petersen, C. Weiler-Normann, Leonard U. Hess, Annika Elise Ahrenstorf, S. Lunemann, G. Martrus, L. Fischer, Jun Li, A. Carambia, J. Kluwe, S. Huber, A. Lohse, A. Franke, J. Herkel, C. Schramm, D. Schwinge   +30 more
semanticscholar   +1 more source

Clinical Features, Differential Diagnosis and Treatment of IgG₄-Related Sclerosing Cholangitis

Архивъ внутренней медицины
The aim: To present the state-of-the-art of clinical features, differential diagnosis and treatment of IgG4-related sclerosing cholangitis.Key points: IgG4-sclerosing cholangitis is a fibrotic inflammatory disease affecting the intrahepatic and ...
A. K. Guseva, A. V. Okhlobystin
doaj   +1 more source

Alterations of the bile microbiome in primary sclerosing cholangitis

Gut, 2019
Background Patients with primary sclerosing cholangitis (PSC) display an altered colonic microbiome compared with healthy controls. However, little is known on the bile duct microbiome and its interplay with bile acid metabolism in PSC.
T. Liwinski, R. Zenouzi, C. John, H. Ehlken, M. Rühlemann, C. Bang, S. Groth, W. Lieb, M. Kantowski, Nils Andersen, G. Schachschal, T. Karlsen, J. Hov, T. Rösch, A. Lohse, J. Heeren, A. Franke, C. Schramm   +17 more
semanticscholar   +1 more source

Survival after liver transplantation in the United Kingdom and Ireland compared with the United States

, 2007
<b>Background and Aim</b>: Surgical mortality in the US is widely perceived to be superior to that in the UK. However, previous comparisons of surgical outcome in the two countries have often failed to take sufficient account of case-mix or ...
Copley, L.P., Dawwas, M.F., Gimson, A.E., Lewsey, J.D., van der Meulen, J.   +4 more
core   +2 more sources

Emerging therapies in primary sclerosing cholangitis: pathophysiological basis and clinical opportunities

Journal of gastroenterology, 2020
Primary sclerosing cholangitis (PSC) is a progressive liver disease, histologically characterized by inflammation and fibrosis of the bile ducts, and clinically leading to multi-focal biliary strictures and with time cirrhosis and liver failure. Patients
M. Vesterhus, T. Karlsen
semanticscholar   +1 more source