Results 101 to 110 of about 575,267 (307)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The effectiveness and cost-effectiveness of opportunistic screening and stepped care interventions for older hazardous alcohol users in primary care (AESOPS) - A randomised control trial protocol [PDF]

, 2008
Background: There is a wealth of evidence regarding the detrimental impact of excessive alcohol consumption. In older populations excessive alcohol consumption is associated with increased risk of coronary heart disease, hypertension, stroke and a range ...
Hassey, A, Tober, G, Drummond, Colin, Parrott, S, Phillips, T, Tober, Gillian, Godfrey, Christine, Raistrick, D, Parrott Steve, Christine Godfrey, Bland, Martin, Rumball, Daphne, Phillips, Tom, Eileen Kaner, Steve Parrott, Watson, J, Coulton, Simon, Parrott, Steve, Colin Drummond, Drummond, C; id_orcid, Rumball, D, Watson, Jude, Coulton, S, Raistrick, Duncan, Coulton Simon, Kaner Eileen, Rumball Daphne, Morton, Veronica, Raistrick Duncan, Phillips Tom, Tom Phillips, Godfrey Christine, Morton Veronica, Bland Martin, Tober Gillian, Hassey, Alan, Morton, V, Kaner, Eileen, Watson Jude, Kaner, E, Gillian Tober, Simon Coulton, Martin Bland, Daphne Rumball, Duncan Raistrick, Philips, Tom, Jude Watson, Hassey Alan, Drummond Colin, Alan Hassey, Godfrey, C, Bland, M, Veronica Morton   +52 more
core   +1 more source

Nursing approach to tobacco users in primary health care

Revista Brasileira de Enfermagem
Objective: to understand the experience of nurses in the approach to tobacco users in primary health care services. Method: Qualitative, phenomenological research with 15 nurses who were interviewed between January and March 2017.
Vanderleia Soéli de Barros Zampier, Marcelo Henrique da Silva, Renata Evangelista Tavares Machado, Rodolfo Ribeiro de Jesus, Maria Cristina Pinto de Jesus, Miriam Aparecida Barbosa Merighi   +5 more
doaj   +1 more source

[User satisfaction in primary care].

Atencion primaria, 1999
To find user satisfaction and assess the usefulness of an analogue scale in measuring satisfaction.Multi-centre, descriptive and crossover study.Four primary care centres in Girona.All those users who happened to attend on a certain day (n = 1349).A multi-dimensional, self-administered and anonymous 33-item questionnaire on satisfaction, which had ...
J C, González Pastor, L, Juandó Perxachs, M, Quesada Sabaté, P, Solanas Saura   +3 more
openaire   +1 more source

Performance analysis of an opportunistic multi‐user cognitive network with multiple primary users

Wireless Communications and Mobile Computing, 2014
AbstractConsider a multi‐user underlay cognitive network where multiple cognitive users concurrently share the spectrum with a primary network with multiple users. The channel between the secondary network is assumed to have independent but not identical Nakagami‐m fading. The interference channel between the secondary users (SUs) and the primary users
Fahd Ahmed Khan, Kamel Tourki, Mohamed-Slim Alouini, Khalid A. Qaraqe   +3 more
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Frequency, factors and costs associated with injection site infections: findings from a national multi-site survey of injecting drug users in England. [PDF]

, 2008
BACKGROUND: Injection site infections among injecting drug users (IDUs) have been associated with serious morbidity and health service costs in North America.
Ncube, F, Ncube, Fortune, Kimber, Jo, Hope, V, Vickerman, Peter, Vickerman, P, Hickman, M, Kimber, J, Hope, Vivian, Hickman, Matthew   +9 more
core   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Polymer Composite Industrial Chemical Pumps [PDF]

, 1998
Tutorialpg. 157Polymers are important materials in the design and application of pumps and piping in many chemical processing systems today. The ability of polymer composites to resist chemical attack is the primary reason for use in industrial equipment,
Cappellino, Charles A., Buse, Frederic W., Rollings, Robert C.   +2 more
core   +1 more source

Perspectives on the HIV continuum of care among adult opioid users in New York City: a qualitative study

Harm Reduction Journal, 2019
Background Engagement in the HIV care continuum combined with office-based opioid treatment remains a cornerstone in addressing the intertwined epidemics of opioid use disorder (OUD) and HIV/AIDS.
Babak Tofighi, Selena S. Sindhu, Chemi Chemi, Crystal Fuller Lewis, Victoria Vaughan Dickson, Joshua D. Lee   +5 more
doaj   +1 more source