Results 111 to 120 of about 575,267 (307)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Dry Running Bellows Type Tandem Seals For VOC Services [PDF]
, 1995 Lecturepg. 83Dry running bellows seal technology, where the secondary (outer) seal operates in a dry condition, was originally developed in the UK and Europe for protection against primary seal failure. Over the past three years, it has been successfully
Kotlyar, Michael +2 more
core +1 more source
Maximum Throughput for a Cognitive Radio Multi-Antenna User with Multiple Primary Users
CoRR, 2014 We investigate a cognitive radio scenario involving a single cognitive transmitter equipped with $\mathcal{K}$ antennas sharing the spectrum with $\mathcal{M}$ primary users (PUs) transmitting over orthogonal bands. Each terminal has a queue to store its incoming traffic.
Ahmed El Shafie 0001, Tamer Khattab
openaire +2 more sources
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Rolling Bearings In Centrifugal Pumps [PDF]
, 1989 Tutorialpg. 91The primary considerations for the selection and application of rolling bearings in centrifugal pumps are discussed. These considerations apply to both the pump manufacturer and the pump user. The various types of bearings used in different
Meyers, Keith E.
core +1 more source
An Active Cooperation-Aware Spectrum Allocation Mechanism for Body Sensor Networks
Sensors, 2015 A cognitive radio-based spectrum allocation scheme using an active cooperative-aware mechanism is proposed in this paper. The scheme ensures that the primary user and secondary users cooperate actively for their own benefits.
Fu Jiang, Ying Guo, Jun Peng, Jiankun Hu
doaj +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
IMPLANTATION OF ACTIONS FOR CONFRONTING DRUG CONSUMPTION IN PRIMARY HEALTH CARE
Cogitare Enfermagem, 2013 The study assessed the implantation of directives for integral care of users of alcohol and other drugs in Primary Health Care, through evaluative research case studies, using the Ministry of Health directives for this public policy.
Jessica Adrielle Teixeira Santos +1 more
doaj +1 more source
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
High Temperature Twin Screw Pumps [PDF]
, 1998 Tutorialpg. 139High temperature applications present many engineering problems. Thermal growth of piping and vessels, coupled with typically lower viscosities at high temperature, has made centerline mounted centrifugal pumps the primary choice in hot ...
Parker, David B.
core +1 more source