Results 71 to 80 of about 2,566,710 (296)

Exploring supervised machine learning approaches to predicting Veterans Health Administration chiropractic service utilization

Chiropractic & Manual Therapies, 2020
Background Chronic spinal pain conditions affect millions of US adults and carry a high healthcare cost burden, both direct and indirect. Conservative interventions for spinal pain conditions, including chiropractic care, have been associated with lower ...
Brian C. Coleman, Samah Fodeh, Anthony J. Lisi, Joseph L. Goulet, Kelsey L. Corcoran, Harini Bathulapalli, Cynthia A. Brandt   +6 more
doaj   +1 more source

Prime languages

Information and Computation, 2013
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Orna Kupferman, Jonathan Mosheiff
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Prime ends for domains in metric spaces

, 2012
In this paper we propose a new definition of prime ends for domains in metric spaces under rather general assumptions. We compare our prime ends to those of Carath\'eodory and N\"akki.
Adamowicz, Ahlfors, Aikawa, Ancona, Ancona, Ancona, Anders Björn, Anderson, Beurling, Björn, Björn, Björn, Björn, Bourbaki, Buckley, Carathéodory, Cheeger, Collingwood, Coulhon, Doob, Durand-Cartagena, Epstein, Garofalo, Grigor’yan, Grigor’yan, Hajłasz, Hajłasz, Hajłasz, Heinonen, Heinonen, Heinonen, Heinonen, Herron, Holopainen, Holopainen, Holopainen, Jana Björn, Järvenpää, Kakutani, Kallunki [Rogovin], Karmazin, Karmazin, Karmazin, Kaufmann, Koskela, Kuratowski, Lewis, Li, Li, Martin, Martio, Mazurkiewicz, Miklyukov, Minda, Nageswari Shanmugalingam, Napier, Newman, Näkki, Näkki, Näkki, Ohtsuka, Perron, Remak, Rempe, Schlesinger, Shanmugalingam, Shanmugalingam, Tomasz Adamowicz, Vuorinen, Väisälä, Väisälä   +70 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

The tree of primes in a field

Cubo, 2010
The product formula of algebraic number theory connects finite and infinite primes in a stringent way, a fact, while not hard to be checked, that has never ceased to be tantalizing.
Wolfgang Rump
doaj  

Probing $W^\prime_L WH$ and $W^\prime_R W H$ Interaction at LHC

, 2011
Many new physics models predict the existence of TeV-scale charged gauge boson $W^\prime$ together with Higgs boson(s). We study the $W^\prime WH$ interaction and explore the angular distribution of charged lepton to distinguish $W_R^\prime WH$ from $W_L^
Bao, Shou-Shan, Li, Hong-Lei, Si, Zong-Guo, Zhou, Yu-Feng   +3 more
core   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source