Results 171 to 180 of about 9,865,590 (355)

Towers of Function Fields over Non-prime Finite Fields [PDF]

arXiv, 2012
Over all non-prime finite fields, we construct some recursive towers of function fields with many rational places. Thus we obtain a substantial improvement on all known lower bounds for Ihara's quantity $A(\ell)$, for $\ell = p^n$ with $p$ prime and $n>3$ odd. We relate the explicit equations to Drinfeld modular varieties.
arxiv  

METTL3 knockout accelerates hepatocarcinogenesis via inhibiting endoplasmic reticulum stress response

FEBS Open Bio, EarlyView.
Liver‐specific knockout of N6‐methyladenosine (m6A) methyltransferase METTL3 significantly accelerated hepatic tumor initiation under various oncogenic challenges, contrary to the previously reported oncogenic role of METTL3 in liver cancer cell lines or xenograft models. Mechanistically, METTL3 deficiency reduced m6A deposition on Manf transcripts and
Bo Cui, Silin Tu, Haibo Li, Zhancheng Zeng, Ruiqi Xiao, Jing Guo, Xiaoqi Liang, Chang Liu, Lijie Pan, Wenjie Chen, Mian Ge, Xiaofen Zhong, Linsen Ye, Huaxin Chen, Qi Zhang, Yan Xu   +15 more
wiley   +1 more source

Skyscraper: Fast Hashing on Big Primes

Transactions on Cryptographic Hardware and Embedded Systems
Arithmetic hash functions defined over prime fields have been actively developed and used in verifiable computation (VC) protocols. Among those, ellipticcurve- based SNARKs require large (256-bit and higher) primes. Such hash functions are notably slow,
Clémence Bouvier, Lorenzo Grassi, Dmitry Khovratovich, Katharina Koschatko, Christian Rechberger, Fabian Schmid, Markus Schofnegger   +6 more
doaj   +1 more source

Proper motions of young stellar outflows in the mid-infrared with Spitzer II HH 377/Cep E

New Journal of Physics, 2014
We have used multiple mid-infrared observations at 4.5 μ m obtained with the infrared array camera, of the compact $(\sim 1.4^{\prime} )$ young stellar bipolar outflow Cep E to measure the proper motion of its brightest condensations.
A Noriega-Crespo, A C Raga, A Moro-Martín, N Flagey, S J Carey   +4 more
doaj   +1 more source

Surprising symmetries in distribution of prime polynomials [PDF]

arXiv, 2015
The primes or prime polynomials (over finite fields) are supposed to be distributed `irregularly' , despite nice asymptotic or average behavior. We provide some conjectures/guesses/hypotheses with `evidence' of surprising symmetries in prime distribution.
arxiv  

On the unramified extensions of the prime cyclotomic number field and its quadratic extensions [PDF]

, 1989
Norikata Nakagoshi
openalex   +1 more source

Co‐expression of HSV‐1 ICP34.5 enhances the expression of gene delivered by self‐amplifying RNA and mitigates its immunogenicity

FEBS Open Bio, EarlyView.
ICP34.5 is one of the most important antihost response proteins. The saRNA‐encoding HSV‐1 neurovirulence protein ICP34.5 clearly mediated the eukaryotic initiation factor 2 alpha subunit (eIF2α) dephosphorylation and significant suppression of innate immune responses in vitro, leading to enhanced expression of the saRNA‐encoded gene.
Xuemin Lu, Yabin Wu, Chunye Zhao, Jie Zheng, Shangwu Chen, Yigang Wang, Yulong Xia   +6 more
wiley   +1 more source

Does the Frobenius endomorphism always generate a direct summand in the endomorphism monoids of fields of prime characteristic? [PDF]

, 1984
Péter Pröhle
openalex   +1 more source

Matrigel inhibits elongation and drives endoderm differentiation in aggregates of mouse embryonic stem cells

FEBS Open Bio, EarlyView.
Stem cell‐based embryo models (SCBEMs) are valuable to study early developmental milestones. Matrigel, a basement membrane matrix, is a critical substrate used in various SCBEM protocols, but its role in driving stem cell lineage commitment is not clearly defined.
Atoosa Amel, Rachel Brown, Alexa Rabeling, Mubeen Goolam   +3 more
wiley   +1 more source

Understanding and Overcoming Immunotherapy Resistance in Skin Cancer: Mechanisms and Strategies

Aging and Cancer, EarlyView.
This narrative review explores the mechanisms driving immunotherapy resistance in skin cancer, including tumor microenvironment factors, genetic mutations, and immune evasion strategies. It highlights potential strategies to overcome resistance, offering insights for improving therapeutic outcomes and guiding future research in personalized ...
Shreya Singh Beniwal, Abhimanyu Chiraparambil Radhakrishnan, Ayanchetty Haripraba, Saif Syed, Gajawada Pragna, Ayush Dwivedi, Akash Rawat, Daniela Castro Calderón, Martin Cevallos‐Cueva   +8 more
wiley   +1 more source